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LAP Lambert Academic Publishing Solubility Enhancement of Fenofibrate by Solid Dispersion Technique: A successful breakthrough for enhancing the release profile of water insoluble drugs

Name: Solubility Enhancement of Fenofibrate by Solid Dispersion Technique: A successful breakthrough for enhancing the release profile of water insoluble drugs
Brand: LAP Lambert Academic Publishing
Price: 61.0 GBP
Availability: InStock

Pharmacology

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Pharmacology

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Description

The poor solubility & low dissolution rate of poorly water soluble drugs in the aqueous gastro-intestinal fluids often cause insufficient bioavailability rather than the limited permeation through the epithelia. With recent progress in high throughput screening of potential therapeutic agents, the number of poorly water-soluble drug candidates has risen sharply & formulating for poorly water-soluble compounds for oral delivery now presents one of the most frequent and greatest challenges to scientists in the pharmaceutical industry. Various formulation strategies have been investigated to improve the solubility and the rate of dissolution to enhance the oral bioavailability of lipophilic drugs. This project work has been designed with purpose to improve the water solubility of water insoluble drug Fenofibrate. Poorly water-soluble drugs often require high doses in order to reach therapeutic plasma concentrations after oral administration. Improvement in the extent and rate of dissolution is highly desirable for such compounds, as this can lead to an increased and more reproducible oral bioavailability and subsequently to clinically relevant dose reduction & more reliable therapy.

Product Specifications

Brand: LAP Lambert Academic Publishing
Format: paperback
ASIN: 620202433X
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Other Branches of Medicine > Pharmacology
Domain: Amazon UK
Release Date: 05 September 2017
Listed Since: 05 October 2017

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LAP Lambert Academic Publishing Solubility Enhancement of Fenofibrate by Solid Dispersion Technique: A successful breakthrough for enhancing the release profile of water insoluble drugs

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It has never been this cheap. We have no record of a lower price.

LAP Lambert Academic Publishing Solubility Enhancement of Fenofibrate by Solid Dispersion Technique: A successful breakthrough for enhancing the release profile of water insoluble drugs

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Price Analysis

Description

Product Specifications

Barcode

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Novel Techniques to Enhance Bioavailability of Poorly Soluble Drugs

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