The Major Approaches for Boosting Aqueous Solubility, Dissolution Rate, and Oral Bioavailability: Development of Solid Dispersion of Insoluble ... Hydrophilic Carriers and Hydrotropic Blends - Image 1

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LAP Lambert Academic Publishing The Major Approaches for Boosting Aqueous Solubility, Dissolution Rate, and Oral Bioavailability: Development of Solid Dispersion of Insoluble ... Hydrophilic Carriers and Hydrotropic Blends

Name: The Major Approaches for Boosting Aqueous Solubility, Dissolution Rate, and Oral Bioavailability: Development of Solid Dispersion of Insoluble ... Hydrophilic Carriers and Hydrotropic Blends
Brand: LAP Lambert Academic Publishing
Price: 71.0 GBP
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Pharmacology

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Poorly water-soluble drugs have emerged as the central challenging aspect that should be probed by scientists during drug development. These obstacles change the way of development of medicines from formulation to overcoming such types of problems. Several methods have been used to treat these limitations. Still, the solid dispersion method is getting the most substantial attention because it can improve the solubility, dissolution rate, and bioavailability of such kinds of drugs effectively. That's why it was recognized as the most effective method for that purpose during drug development. Antihyperlipidemic agent atorvastatin calcium (ATV) faced a problem after oral administration due to low water solubility characteristics. Boosting the solubility and oral bioavailability of such kinds of drugs are the major obstacles that formulation scientists faced. This Study’s aim was to enhance the solubility and dissolution rate of ATV by the formation of solid dispersion-based hydrotropic blends. Solid dispersion-based hydrotropic blends can result in the production of the dosage forms of practically insoluble drugs with an optimum enhancement ratio in their solubility.

Product Specifications

Brand: LAP Lambert Academic Publishing
Format: paperback
ASIN: 6205640856
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Other Branches of Medicine > Pharmacology
Domain: Amazon UK
Release Date: 13 February 2023
Listed Since: 09 March 2023

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LAP Lambert Academic Publishing The Major Approaches for Boosting Aqueous Solubility, Dissolution Rate, and Oral Bioavailability: Development of Solid Dispersion of Insoluble ... Hydrophilic Carriers and Hydrotropic Blends

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It has never been this cheap. We have no record of a lower price.

LAP Lambert Academic Publishing The Major Approaches for Boosting Aqueous Solubility, Dissolution Rate, and Oral Bioavailability: Development of Solid Dispersion of Insoluble ... Hydrophilic Carriers and Hydrotropic Blends

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Description

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