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ACADEMIQUES Les entérocoques résistants à la vancomycine: De la diversité à la clonalité Détection et typage

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Description

Cet ouvrage analyse l'évolution des souches épidémiques d'Enterococcus faecium résistants à la vancomycine dans les hôpitaux français depuis 2006, à l'aide de différentes méthodes moléculaires et évalue des techniques émergentes de typage et de détection. La technique de MLST (Multi-Locus Sequence Typing) a permis de confirmer que les souches hospitalières appartiennent au complexe clonal 17 (CC17). Différents Sequence Type (ST) sont impliqués dans les épidémies sans qu'il ait été possible d'identifier un ST plus particulièrement virulent. L'émergence des souches d'Enterococcus faecalis résistantes à la vancomycine et à de hauts niveaux de gentamicine a été également mis en évidence. Elles constituent un groupe particulier de souches appartenant toutes au CC2, où la présence de facteurs de virulence est plus fréquente. Une technique entièrement automatisée de PCR permettant la détection de gènes de résistance à la vancomycine dans les selles a été évaluée ainsi qu’une technique de typage automatisée basée sur la rep-PCR pour identifier les souches épidémiques.

Product Specifications

Format
paperback
Domain
Amazon UK
Release Date
24 November 2014
Listed Since
18 December 2014

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