Advancements in Lung Cancer Surgical Treatment and Prognosis

Lung cancer remains a leading cause of cancer-related mortality worldwide, yet recent advances are reshaping its surgical and multidisciplinary management. Progress in minimally invasive and robotic surgical techniques, improved perioperative strategies, molecularly targeted therapies, and immunotherapy has fundamentally altered treatment paradigms and patient outcomes. At the same time, advances in staging, molecular diagnostics, and trial design have enabled more precise and individualized care. This Reprint presents an up-to-date overview of contemporary lung cancer management with a particular focus on surgery and its integration with systemic therapies. It highlights innovations in surgical technique, perioperative decision-making, and prognostic assessment, alongside the growing role of molecular profiling and immune-based treatments. Emphasis is placed on accurate staging, early molecular characterization, and the translation of recent clinical trial data into clinical practice. Collectively, the articles in this Reprint provide a comprehensive perspective on current standards of care, emerging strategies, and future directions in lung cancer treatment. By integrating surgical, medical, and translational insights, this Reprint aims to inform clinicians and researchers about the evolving landscape of lung cancer care and the multidisciplinary approaches that are defining the next era of outcomes improvement.