Novel use of Thymol and Carvacrol: Evaluation of possible protective effects of thymol and carvacrol against cisplatin-induced nephrotoxicity in rats - Image 1

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LAP Lambert Academic Publishing Novel use of Thymol and Carvacrol: Evaluation of possible protective effects of thymol and carvacrol against cisplatin-induced nephrotoxicity in rats

Name: Novel use of Thymol and Carvacrol: Evaluation of possible protective effects of thymol and carvacrol against cisplatin-induced nephrotoxicity in rats
Brand: LAP Lambert Academic Publishing
Price: 54.0 GBP
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Biological Science

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Description

The main dose-limiting side effect of cisplatin (CP) is nephrotoxicity. Yet, in spite of intense efforts over the ensuing decades to find less toxic but equally effective alternatives, CP continues to be widely prescribed. It remains as a standard component of treatment regimens for head and neck cancers, testicular cancer, small-cell and non-small cell lung cancer, ovarian, cervical cancer, bladder cancer and others. Monoterpenes are highly hydrophobic substances present in plant essential oils. They exert a wide spectrum of biological actions of great importance in many different areas. Two monoterpenes of the Lamiaceae that have attracted much attention, thymol and carvacrol. Hence, this study was aimed to investigate the efficacy of thymol and CAR or their combination in ameliorating the toxic effects via inhibition of oxidative damage, inflammation and apoptosis induced by CP in rats.

Product Specifications

Brand: LAP Lambert Academic Publishing
Format: paperback
ASIN: 3659712477
Category: Books > Subjects > Science, Nature & Maths > Biological Sciences > Biological Science
Domain: Amazon UK
Release Date: 04 June 2015
Listed Since: 29 June 2015

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LAP Lambert Academic Publishing Novel use of Thymol and Carvacrol: Evaluation of possible protective effects of thymol and carvacrol against cisplatin-induced nephrotoxicity in rats

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