Springer Phosphoinositide 3-kinase in Health and Disease: Volume 1: 346 (Current Topics in Microbiology and Immunology, 346)

Product Description PI3K is at the forefront of drug development with the first clinical trials of PI3K pathway inhibitors in progress. This book offers an overview of some key discoveries in the PI3K area and their impact, and includes thoughts on the current state of the field. From the Back Cover From humble beginnings over 25 years ago as a lipid kinase activity associated with certain oncoproteins, PI3K (phosphoinositide 3-kinase) has been catapulted to the forefront of drug development in cancer, immunity and thrombosis, with the first clinical trials of PI3K pathway inhibitors now in progress. Here the authors give a brief overview of some key discoveries in the PI3K area and their impact, and include thoughts on the current state of the field, and where it could go from here.