Death Receptors and Cognate Ligands in Cancer: 49 (Results and Problems in Cell Differentiation, 49) - Image 1

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Springer Death Receptors and Cognate Ligands in Cancer: 49 (Results and Problems in Cell Differentiation, 49)

Name: Death Receptors and Cognate Ligands in Cancer: 49 (Results and Problems in Cell Differentiation, 49)
Brand: Springer

General Medical Issues

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Product Description Death receptors play a central role in directing apoptosis in mammalian cells. This book explores the molecular basis of death receptor signaling and their role in cancer development. From the Back Cover Death receptors play a central role in directing apoptosis in mammalian cells. This process of active cell death is important for a number of biological processes, e.g. for the regulation of the immune system. Death receptors are cell surface receptors that transmit apoptotic signals initiated by corresponding death ligands. Many complex signaling pathways are activated and apoptosis is the final result of a complex biochemical cascade of events. Besides their role in the induction of cell death, evidence now exists that death receptors are able to activate several non-apoptotic signaling pathways which, depending on cellular context, may lead to apoptosis resistance, secretion of pro-inflammatory proteins, proliferation and invasive growth of cancer cells. This book looks at the molecular basis of death receptor signaling and the role of death receptors in cancer development.

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Brand: Springer
Format: paperback
ASIN: 3642260764
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > General Medical Issues
Domain: Amazon UK
Release Date: 14 March 2012
Listed Since: 08 March 2012

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Springer Death Receptors and Cognate Ligands in Cancer: 49 (Results and Problems in Cell Differentiation, 49)

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