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£91.61

Wiley Inducing Targeted Protein Degradation: From Chemical Biology to Drug Discovery and Clinical Applications

Name: Inducing Targeted Protein Degradation: From Chemical Biology to Drug Discovery and Clinical Applications
Brand: Wiley
Price: 91.66 GBP
Availability: InStock

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Inducing Targeted Protein Degradation Enables drug developers in academia and industry to expand the range of accessible drug targets through induced protein degradation Since the breakthrough of the PROTAC technology in 2015, targeted protein degradation has revolutionized drug discovery, enabling pharma companies to develop completely novel therapeutics. Inducing Targeted Protein Degradation is a timely guide to navigating the complexities of the subject and understanding its practical application, with an eye on expanding the druggable space. In Inducing Targeted Protein Degradation, readers will find the most recent information on: Cellular mechanisms of targeted protein degradation and current approaches to utilize these mechanisms for drug discovery A comparison of different induced degradation approaches, including PROTAC, molecular glues, LYTACs and ATTECs as well as additional post translational modifications Drug development aspects such as DMPK optimization and criteria for the selection of clinical candidates A discussion of the potential of targeted degradation for expanding the druggable space Inducing Targeted Protein Degradation will serve as a practice-oriented reference on induced protein degradation for drug discovery professionals and for researchers employing chemical biology approaches.

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Brand: Wiley
Format: hardcover
ASIN: 3527350136
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Other Branches of Medicine
Domain: Amazon UK
Release Date: 28 December 2022
Listed Since: 03 June 2021

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Wiley Inducing Targeted Protein Degradation: From Chemical Biology to Drug Discovery and Clinical Applications

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