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Humana Targeted Protein Degradation: Methods and Protocols 2365

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Description

Expand your laboratory capabilities with Targeted Protein Degradation: Methods and Protocols, volume 2365 of the Methods in Molecular Biology series. This comprehensive volume provides a collection of innovative techniques designed for researchers studying modern protein degradation pathways. This book offers detailed guidance on heterobifunctional proteolysis-targeting chimeras (PROTACs) approaches and E3 ligase-induced ubiquitylation. You will find technical information regarding proteomic approaches, novel degrader molecules, and molecular glue methods used to stabilize binding interactions between a target and E3 ubiquitin ligase. Written in the proven Methods in Molecular Biology format, each chapter is structured to support practical laboratory work. The content includes necessary introductions to specific topics, essential lists of materials and reagents, and helpful tips for troubleshooting common experimental issues. This makes it a reliable resource for scientists working in molecular biology and drug discovery.

Key Features

Comprehensive coverage of PROTACs approaches and E3 ligase-induced ubiquitylation techniques.

Technical guidance on proteomic approaches and the use of novel degrader molecules.

Detailed instructions on molecular glue methods to stabilize target and E3 ubiquitin ligase binding.

Practical chapter structure including necessary materials and reagents lists for lab readiness.

Includes troubleshooting tips to help navigate common experimental challenges in protein degradation research.

Product Specifications

Brand
Humana
Format
paperback
Domain
Amazon UK
Release Date
26 August 2021
Listed Since
30 July 2022

Barcode

No barcode data available

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