Functionally Relevant Macromolecular Interactions of Disordered Proteins - Image 1

£72.00

MDPI AG Functionally Relevant Macromolecular Interactions of Disordered Proteins

Name: Functionally Relevant Macromolecular Interactions of Disordered Proteins
Brand: MDPI AG
Price: 70.72 GBP
Availability: InStock

Biological Science

Price History & Forecast

Last 34 days • 34 data points (No recent data available)

Historical

Generating forecast...

Price Distribution

Price distribution over 34 days • 2 price levels

Days at Price

Current Price

Price Analysis

Most common price: £71 (20 days, 58.8%)

Price range: £71 - £72

Price levels: 2 different prices over 34 days

Description

Disordered proteins are relatively recent newcomers in protein science. They were first described in detail by Wright and Dyson, in their J. Mol. Biol. paper in 1999. First, it was generally thought for more than a decade that disordered proteins or disordered parts of proteins have different amino acid compositions than folded proteins, and various prediction methods were developed based on this principle. These methods were suitable for distinguishing between the disordered (unstructured) and structured proteins known at that time. In addition, they could predict the site where a folded protein binds to the disordered part of a protein, shaping the latter into a well-defined 3D structure. Recently, however, evidence has emerged for a new type of disordered protein family whose members can undergo coupled folding and binding without the involvement of any folded proteins. Instead, they interact with each other, stabilizing their structure via "mutual synergistic folding" and, surprisingly, they exhibit the same residue composition as the folded protein. Increasingly more examples have been found where disordered proteins interact with non-protein macromolecules, adding to the already large variety of protein-protein interactions. There is also a very new phenomenon when proteins are involved in phase separation, which can represent a weak but functionally important macromolecular interaction. These phenomena are presented and discussed in the chapters of this book.

Product Specifications

Brand: MDPI AG
Format: Hardcover
ASIN: 3039365215
Category: Books > Subjects > Science, Nature & Maths > Biological Sciences > Biological Science
Domain: Amazon UK
Release Date: 24 August 2020
Listed Since: 27 August 2020

Barcode

No barcode data available

MDPI AG Functionally Relevant Macromolecular Interactions of Disordered Proteins

Price History & Forecast

Price Distribution

Price Analysis

Description

Product Specifications

Barcode

Similar Products You Might Like

The Physics of Protein Structure and Dynamics: When and Why Proteins Fold or Don’t Fold

Structure and Function of Intrinsically Disordered Proteins

The Three Functional States of Proteins: Structured, Intrinsically Disordered, and Phase Separated

Unfolded Proteins: From Denatured to Intrinsically Disordered

Academic Press Dancing Protein Clouds - Volume 166

Computational Approaches to Protein Dynamics: From Quantum to Coarse-Grained Methods (Series in Computational Biophysics)

Intrinsically Disordered Proteins Studied by NMR Spectroscopy: 870 (Advances in Experimental Medicine and Biology, 870)

Academic Press Dancing Protein Clouds Volume 174 - Part B

The Protein Folding Problem

Springer - Folding of Disulfide Proteins (Protein Reviews, 14)

Bio-Nanoimaging: Protein Misfolding & Aggregation

Theory of Phase Transitions in Polypeptides and Proteins (Springer Theses)

Intrinsically Disordered Proteins (Volume 611) (Methods in Enzymology, Volume 611)

Protein Physics: A Course of Lectures (Soft Condensed Matter, Complex Fluids and Biomaterials)

Theory of Phase Transitions in Polypeptides and Proteins (Springer Theses)

Springer - Physical Biology of Proteins and Peptides Book

The Molecular Chaperones Interaction Networks in Protein Folding and Degradation: 1 (Interactomics and Systems Biology, 1)

Springer Intrinsically Disordered Protein Analysis Vol 2

Intrinsically Disordered Proteins: Methods and Protocols: 2141 (Methods in Molecular Biology, 2141)

Springer - Frontiers in Protein Structure, Function, and Dynamics

Springer Protein Conformational Dynamics: 805 - Biology Book

Protein Interactions: Biophysical Approaches for the Study of Complex Reversible Systems: 5 (Protein Reviews, 5)

Intrinsically Disordered Protein Analysis: Volume 1, Methods and Experimental Tools: 895 (Methods in Molecular Biology, 895)

Humana Protein Misfolding and Disease: 232 Methods in Molecular Biology