£91.40

About as cheap as it gets — within 5% of the all-time low it hit 2 months ago.

£91 today · all-time low £88 (Aug 2026) · usually £91

Nova Science Publishers Inc Fanconi Anemia & Oxidative Stress: Mechanistic Background & Clinical Prospects

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£105.30 £86.57 £90.65 £94.74 £98.83 £102.92 £107.00 25 July 2026 16 August 2026 07 September 2026 29 September 2026 21 October 2026
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13 days 4 days 30 days 14 days 11 days · current 17 days 0 8 15 23 30 £88 £89 £90 £91 £92 £105 Days at Price

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Most common price: £90 (30 days, 33.7%)

Price range: £88 - £105

Price levels: 6 different prices over 89 days

Description
Fanconi Anemia (FA), a rare genetic disease featuring excess cancer risk and chromosomal instability, has received growing interest after the discovery that one of the defective genes in FA is associated with high-impact diseases such as familial breast cancer and ovary cancers. A well-documented relationship has accumulated in several decades and up to recently, studies have linked FA with a redox imbalance (oxidative stress, OS) in FA cells. The toxicity mechanisms of crosslinking agents (mitomycin C and diepoxybutane) in FA cells, along with the roles of OS-related aldehydes and glutathione in FA and in other diseases, are critically discussed. Also discussed is the proinflammatory state in FA phenotype. Additionally, recent studies have discovered an impairment in the structure and function of mitochondria in FA cell lines, while mitochondrial dysfunction in FA patients has so far been an unexplored field warranting ad hoc investigations. This book provides the readers with up-to-date information and perspectives on Fanconi anemia and oxidative stress that may prompt further elucidation of this intriguing disease, along with working hypotheses in clinical research and patients' management.

Product Specifications
Brand
Nova Science Publishers Inc
Format
hardcover
ASIN
1634822978
Category
Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Internal Medicine > Diseases & Disorders > Oncology
Domain
Amazon UK
Release Date
01 June 2015
Listed Since
21 February 2015

Barcode

No barcode data available

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