£69.83

KAINIC ACID NEUROTOXIC PROPERTIES BI: Neurotoxic Properties, Biological Sources & Clinical Applications (Biochemistry Research Trends)

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Last 617 days • 617 data points (No recent data available)

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£93.21 £64.69 £70.91 £77.13 £83.36 £89.58 £95.80 12 June 2024 13 November 2024 16 April 2025 17 September 2025 18 February 2026

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154 days · current 160 days 205 days 98 days 0 51 103 154 205 £67-72 £72-78 £78-83 £88-93 Days at Price

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Most common range: £78-83 (205 days, 33.2%)

Price range: £67 - £93

Price levels: 4 price ranges over 617 days

Description

Kainic acid is a naturally occurring amino acid that is isolated from red algae and is known to cause amnesic shellfish poisoning via the activation of AMPA and kainate receptors in the hippocampus. Kainic acid is an analogue of glutamate and can modulate the transmission of glutamate. It's neurotoxic potency has been shown to be 30 fold that of glutamate. Glutamate is an excitatory neurotransmitter that exerts its postsynaptic effects through ionotropic and metabotropic receptors. Of the ionotropic glutamate receptors (GluRs), kainic acid has a high affinity for 5 subtypes (KA1 and KA2, GluR5, GluR6, GluR7). Kainate receptors play a significant role in the physiological functioning and activity of numerous systems in the brain. This book discusses the neurotoxic properties of kainic acid, as well as the biological sources and clinical applications.

Product Specifications

Format
hardcover
Domain
Amazon UK
Release Date
01 June 2014
Listed Since
04 April 2014

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