£14.04

Alkylating Agents as Environmental Carcinogen & Chemotherapy Agents (Cell Biology Research Progress: Cancer Etiology, Diagnosis and Treatments)

Price data last checked 71 day(s) ago - refreshing...

View at Amazon

We'll watch every seller, every day. One email when your price arrives.

This is the usual price. Wait for it to drop, or tell us your number.

£14 today · usual range £13–£18 · best ever £13

NEW HERE?

Amazon shows you one price. We show you all of them.

Tosheroon watches Amazon prices so you don't have to. Every product on Amazon has a price history — we make it visible. Set the price you'd actually pay, and we'll email you the second it gets there. No app, no account, one email.

WHAT'S ON THIS PAGE

↓ Price chart
when this has been cheap or pricey
↓ Forecast
where the price is heading next
↓ Statistics
all-time high & low, recent range
↑ Price alert
name your number, we'll email you

Price History & Forecast

Grey patches = out of stock. Cheaper = lower on the chart. Hover for exact prices.

Last 20 days • 20 data points (No recent data available)

Historical
Generating forecast...
£17.92 £12.65 £13.80 £14.95 £16.10 £17.25 £18.40 09 April 2026 13 April 2026 18 April 2026 23 April 2026 28 April 2026

Price Distribution

Price distribution over 20 days • 3 price levels

Days at Price
Current Price
12 days 1 day · current 7 days 0 3 6 9 12 £13 £14 £18 Days at Price

Price Analysis

Most common price: £13 (12 days, 60.0%)

Price range: £13 - £18

Price levels: 3 different prices over 20 days

Description

Alkylating agents are an important class of carcinogens. O6-methylguanine (O6 MG) formed in cellular DNA by alkylating agents is a mutagenic lesion. Reactive metabolites, which are capable of alkylate in the DNA base, are produced during the catabolism of precursors of alkylating agents in the diet. Active alkylating agents can also be synthesised endogenously in the body. Endogenous alkylating agents are produced via nitrosation of primary amines by nitrates and nitrous anhydride formed by nitric oxide. Exposure of alkylating agents is at a minimum level in daily life. On the other hand, alkylating agents are used in certain chemotherapy regimens. Various investigators determined that O6-MGMT is at a high level in human tumours, thus they exhibit resistance to chemotherapy, including alkylating agents. Various anaolgs of O6-MG were suggested as a potential adjuvant in combination chemotherapy with alkylating agents to treat O6-MGMT proficient tumours. The susceptibility of any tissue to mutagenic effect of alkylating agents is dependent upon the balance between the ability of the tissue to metabolise alkylating agents to carcinogenic intermediates, the extent of O6-MG formation, rate of repair by O6-MGMT, and the extent of DNA replication which occurs when O6-MG is present. This book is a reliable reference for the sources of alkylating agents and their effects in human body.

Product Specifications

Format
hardcover
Domain
Amazon UK
Release Date
01 July 2013
Listed Since
14 March 2013

Barcode

No barcode data available

Similar Products You Might Like

Metabolism and Epigenetic Regulation: Implications in Cancer: 100 (Subcellular Biochemistry, 100)
95% match

Metabolism and Epigenetic Regulation: Implications in Cancer: 100 (Subcellular Biochemistry, 100)

Springer

£179.98 03 May 2026
Development of New Radical Cascades and Multi-Component Reactions: Application to the Synthesis of Nitrogen-Containing Heterocycles (Springer Theses)
95% match

Development of New Radical Cascades and Multi-Component Reactions: Application to the Synthesis of Nitrogen-Containing Heterocycles (Springer Theses)

Springer

£76.38 04 Jul 2026
Development of New Radical Cascades and Multi-Component Reactions: Application to the Synthesis of Nitrogen-Containing Heterocycles (Springer Theses)
95% match

Development of New Radical Cascades and Multi-Component Reactions: Application to the Synthesis of Nitrogen-Containing Heterocycles (Springer Theses)

Springer

£72.98 08 Mar 2026
CRC Press Mutagens in Food - Chemical Science Reference Book
95% match

CRC Press Mutagens in Food - Chemical Science Reference Book

CRC Press

£175.02 04 Jul 2026
Mutant p53 and MDM2 in Cancer: 85 (Subcellular Biochemistry, 85)
95% match

Mutant p53 and MDM2 in Cancer: 85 (Subcellular Biochemistry, 85)

Springer

£95.76 23 Apr 2026
Springer Mutant p53 and MDM2 in Cancer - Subcellular Biochemistry 85
95% match

Springer Mutant p53 and MDM2 in Cancer - Subcellular Biochemistry 85

Springer

£112.81 30 Apr 2026
Carbon-Carbon ?-Bond Formation: Volume 3 (Comprehensive Organic Synthesis II - Online)
95% match

Carbon-Carbon ?-Bond Formation: Volume 3 (Comprehensive Organic Synthesis II - Online)

Pergamon

£390.00 10 Jun 2026
Alkanes: Properties, Production and Applications (Chemistry Research and Applications)
95% match

Alkanes: Properties, Production and Applications (Chemistry Research and Applications)

£137.77 17 Jun 2026
Practical Organic Chemistry: A student handbook of techniques
94% match

Practical Organic Chemistry: A student handbook of techniques

Springer

£44.98 02 Jul 2026
Industrial Organic Chemicals
94% match

Industrial Organic Chemicals

Wiley

£94.47 16 Jun 2026
Organic Syntheses, Volume 79
94% match

Organic Syntheses, Volume 79

Wiley

£70.08 04 Jul 2026
Carbenes nitrenes and arynes (Studies in Modern Chemistry)
94% match

Carbenes nitrenes and arynes (Studies in Modern Chemistry)

Springer

£70.01 27 Apr 2026
Nitrile Oxides, Nitrones and Nitronates in Organic Synthesis: Novel Strategies in Synthesis: 6 (Organic Nitro Chemistry)
94% match

Nitrile Oxides, Nitrones and Nitronates in Organic Synthesis: Novel Strategies in Synthesis: 6 (Organic Nitro Chemistry)

Wiley

£194.39 13 Jun 2026
Organic Chemistry: Structure, Mechanism, Synthesis
94% match

Organic Chemistry: Structure, Mechanism, Synthesis

Academic Press

£152.25 13 Jun 2026
d-Orbitals in the Chemistry of Silicon, Phosphorus and Sulfur: 3 (Reactivity and Structure: Concepts in Organic Chemistry, 3)
94% match

d-Orbitals in the Chemistry of Silicon, Phosphorus and Sulfur: 3 (Reactivity and Structure: Concepts in Organic Chemistry, 3)

Springer

£74.86 06 Jul 2026
Cancer Epigenetics for Precision Medicine: Methods and Protocols: 1856 (Methods in Molecular Biology, 1856)
94% match

Cancer Epigenetics for Precision Medicine: Methods and Protocols: 1856 (Methods in Molecular Biology, 1856)

Humana

£117.75 27 Jun 2026
CRC Press Advanced Practical Organic Chemistry - 3rd Edition
94% match

CRC Press Advanced Practical Organic Chemistry - 3rd Edition

CRC Press

£175.94 07 May 2026
Mechanisms of Environmental Mutagenesis-Carcinogenesis (Mechanisms of Environmental Mutagenesis-carcinogenesis: Meeting Proceedings)
94% match

Mechanisms of Environmental Mutagenesis-Carcinogenesis (Mechanisms of Environmental Mutagenesis-carcinogenesis: Meeting Proceedings)

Springer

£34.44 27 Jun 2026
Molecular mechanisms and physiology of disease: Implications for Epigenetics and Health
94% match

Molecular mechanisms and physiology of disease: Implications for Epigenetics and Health

Springer

£98.49 16 Jun 2026
Springer Resorcinol: Its Uses and Derivatives Chemistry Book
94% match

Springer Resorcinol: Its Uses and Derivatives Chemistry Book

Springer

£108.42 13 May 2026
Pollutant-Solid Phase Interactions Mechanisms, Chemistry and Modeling: 5 / 5E (The Handbook of Environmental Chemistry, 5 / 5E)
94% match

Pollutant-Solid Phase Interactions Mechanisms, Chemistry and Modeling: 5 / 5E (The Handbook of Environmental Chemistry, 5 / 5E)

Springer

£146.56 10 Mar 2026
Springer Pollutant-Solid Phase Interactions Handbook - 5/5E
94% match

Springer Pollutant-Solid Phase Interactions Handbook - 5/5E

Springer

£145.76 06 May 2026
Humana - Targeting the DNA Damage Response for Anti-Cancer Therapy
94% match

Humana - Targeting the DNA Damage Response for Anti-Cancer Therapy

Humana

£147.11 29 Apr 2026
Hydroxamic Acids: A Unique Family of Chemicals with Multiple Biological Activities
94% match

Hydroxamic Acids: A Unique Family of Chemicals with Multiple Biological Activities

Springer

£77.62 02 May 2026