Von Willebrand Disease: Diagnosis and Management: Diagnosis & Management (Recent Advances in Hematology Research: Public Health in the 21st Century)

von Willebrand disease (VWD) is an inherited bleeding disorder that is caused by deficiency or dysfunction of von Willebrand factor (VWF), a plasma protein that mediates the initial adhesion of platelets at sites of vascular injury and also binds and stabilizes blood clotting factor VIII (FVIII) in the circulation. This book examines the need for more information on VWD prevalence and the relationship between low VWF levels of bleeding symptoms or risk and improving clinical and laboratory diagnostic tools.