Detection of anti-ADAMTS13 antibodies in patients with TTP: Characterization of the immune response against ADAMTS13 in patients with thrombotic thrombocytopenic purpura - Image 1

£48.00

Südwestdeutscher Verlag für Hochschulschriften Detection of anti-ADAMTS13 antibodies in patients with TTP: Characterization of the immune response against ADAMTS13 in patients with thrombotic thrombocytopenic purpura

General Medical Issues

Price data last checked 121 day(s) ago - refreshing...

View at Amazon

We'll watch every seller, every day. One email when your price arrives.

It has never been this cheap. We have no record of a lower price.

£48 today · cheaper than every other day in the last 24 months

NEW HERE?

Amazon shows you one price. We show you all of them.

Tosheroon watches Amazon prices so you don't have to. Every product on Amazon has a price history — we make it visible. Set the price you'd actually pay, and we'll email you the second it gets there. No app, no account, one email.

WHAT'S ON THIS PAGE

↓ Price chart
when this has been cheap or pricey

↓ Forecast
where the price is heading next

↓ Statistics
all-time high & low, recent range

↑ Price alert
name your number, we'll email you

Price History & Forecast

Grey patches = out of stock. Cheaper = lower on the chart. Hover for exact prices.

Last 610 days • 610 data points (No recent data available)

Historical

Generating forecast...

Price Distribution

Price distribution over 610 days • 1 price levels

Days at Price

Price Analysis

Most common price: £48 (610 days, 100.0%)

Price range: £48 - £48

Price levels: 1 different prices over 610 days

Description

Thrombotic thrombocytopenic purpura (TTP) is a life-threatening disease caused by a deficiency in ADAMTS13 which in the acquired form is provoked by autoantibodies against this protease. The main objective of this work was to study the pathophysiologic and prognostic value of anti-ADAMTS13 antibodies in patients with acquired TTP. The surveyed antibody profile revealed the presence of mainly IgG followed by IgA and IgM antibodies. IgG1-4 and IgA ADAMTS13-specific immune complex (ICs) were detected. IgG4 was the most prevalent IgG subclass, present either as free antibody or as ICs. IgG antibodies in combination with high inhibitor titers at disease presentation were associated with persistence of undetectable ADAMTS13 activity in clinical remission. TTP patients with high IgG4 and undetectable IgG1 levels were more prone to relapse than patients with low IgG4 and detectable IgG1 levels suggesting that IgG4 could be a useful biomarker for identification of patients at risk of disease recurrence. The comprehensive characterization of anti-ADAMTS13 antibodies as well as circulating ADAMTS13-specific ICs may contribute to a better understanding of the mechanisms leading to acquired TTP About the Author Master degrees in Biochemistry and Pharmaceutical Chemistry; University of Córdoba, Argentina. PhD degree in Natural Science, Molecular Biology; University of Vienna, Austria. Supervisor in the R&D area at Baxter Innovations; Vienna, Austria. More than ten years of clinical and research experience in the field of Hemostasis.

Product Specifications

Brand: Südwestdeutscher Verlag für Hochschulschriften
Format: paperback
ASIN: 3838138627
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > General Medical Issues
Domain: Amazon UK
Publication Date: 27 May 2014
Listed Since: 19 June 2014

Barcode

No barcode data available

Südwestdeutscher Verlag für Hochschulschriften Detection of anti-ADAMTS13 antibodies in patients with TTP: Characterization of the immune response against ADAMTS13 in patients with thrombotic thrombocytopenic purpura

It has never been this cheap. We have no record of a lower price.

Price History & Forecast

Price Distribution

Price Analysis

Description

Product Specifications

Barcode

Similar Products You Might Like

Hemostasis and Thrombosis: Methods and Protocols: 1646 (Methods in Molecular Biology, 1646)

Ace The Boards: Non - Neoplastic Hematopathology and Coagulation (Ace My Path)

Autoimmune Thrombocytopenia

Essential Guide to Blood Coagulation, 2nd Edition

The Coagulation Consult: A Case-Based Guide

The Coagulation Consult: A Case-Based Guide

Transfusion Medicine and Hemostasis: Clinical and Laboratory Aspects

Platelets and Megakaryocytes: Volume 4, Advanced Protocols and Perspectives: 1812 (Methods in Molecular Biology, 1812)

Hemophilia and Hemostasis: A Case-Based Approach to Management

Laboratory Techniques in Thrombosis ― a Manual (2nd Revised Edition of Ecat Assay Procedures)

Antiphospholipid Syndrome: Current Research Highlights and Clinical Insights

Antiphospholipid Syndrome: Current Research Highlights and Clinical Insights

Hemostasis and Thrombosis: Basic Principles and Clinical Practice

SickKids Handbook of Pediatric Thrombosis and Hemostasis

Quality in Laboratory Hemostasis and Thrombosis

Autoimmune Thrombocytopenia

Cambridge University Press - Blood Coagulation and Complement System

Disorders of Hemostasis & Thrombosis: A Clinical Guide (HEMATOLOGY/ONCOLOGY)

Dacie and Lewis Practical Haematology: Expert Consult: Online and Print

Platelet Glycoprotein IIb/IIIa Inhibitors in Cardiovascular Disease (Contemporary Cardiology)

Congenital Bleeding Disorders: Diagnosis and Management

Congenital Bleeding Disorders: Diagnosis and Management

New Trends in Haemostasis: Coagulation Proteins, Endothelium, and Tissue Factors: 1990 / 1990/3 (Sitzungsberichte der Heidelberger Akademie der Wissenschaften, 1990 / 1990/3)

Blut und Blutkrankheiten: Teil 9 Blutgerinnung und Hämorrhagische Diathesen II Angeborene und Erworbene Koagulopathien: 2 / 9 (Handbuch der inneren Medizin, 2 / 9)