£199.99

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£200 today · previous high £200 · all-time low £195

Humana Chemical Carcinogenesis (Current Cancer Research)

Amazon

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£199.99 £194.49 £195.69 £196.89 £198.09 £199.29 £200.49 25 July 2026 09 August 2026 25 August 2026 09 September 2026 25 September 2026
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Most common price: £200 (32 days, 50.8%)

Price range: £195 - £200

Price levels: 2 different prices over 63 days

Description
This volume will provide a contemporary account of advances in chemical carcinogenesis. It will promote the view that it is chemical alteration of the DNA that is a route cause of many cancers. The multi-stage model of chemical carcinogenesis, exposure to major classes of human carcinogens and their mode-of-action will be a focal point. The balance between metabolic activation to form biological reactive intermediates and their detoxification, ensuing DNA-lesions and their repair will be profiled. It will describe the chemical changes that occur in DNA that result from endogenous insults including epigenetic changes that lead to gene silencing. It will describe major mechanisms of mutagenesis, affects on tumor suppressor genes and proto-oncogenes, and how cell-cycle check points can be by-passed by the "stealth-like" properties of chemical carcinogens. Environmental agents that can promote tumor formation will be discussed. The monograph will have wide appeal as a knowledge base for graduate students, post-doctoral fellows and faculty interested in this aspect of cancer causation and research.

Product Specifications
Brand
Humana
Format
hardcover
ASIN
1617379948
Category
Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Internal Medicine > Diseases & Disorders
Domain
Amazon UK
Release Date
03 March 2011
Listed Since
24 September 2010

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