Humana Inflammation and Cancer: Methods and Protocols: Volume 2, Molecular Analysis and Pathways: 512 (Methods in Molecular Biology, 512)

One out of seven newly diagnosed malignancies worldwide result from infection and chronic inflammation in conjunction with cancer. This book is a guide for fighting the 2,200 inflammation-related oncogenesis fatalities that occur every day. Review From the reviews: “Chapters in this volume are designed to be guides to techniques addressing various aspects of experimental cancer biology. … this volume will earn a place on the lab benches of investigators and clinicians who are studying inflammation-related oncogenesis. … this book can provide a source of information for establishing new techniques as well as suggestions for investigating particular aspects of tumorigenesis.” (Marion C. Cohen, Doody’s Review Service, December, 2009) From the Back Cover According to the most recent clinical oncology data, one out of seven newly diagnosed malignancies worldwide result from infection and chronic inflammation in conjunction with cancer.  In Inflammation and Cancer: Methods and Protocols, expert researchers deliver a systematic guide to techniques addressing various aspects of experimental cancer biology, selectively focused on inflammation-mediated tumorigenesis, while promoting improvisations on a per-case basis. Volume 2, Molecular Analysis and Pathways is devoted to an extensive description of experimental strategies aimed at investigating the molecular cross-talks between components of cell signaling chains and their ramifications in diagnostic development and drug target discovery. Written in the highly successful Methods in Molecular Biology™ series format, chapters include brief introductions to their subjects, lists of the necessary materials and reagents, step-by-step laboratory protocols, and a notes section, which examines tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Inflammation and Cancer: Methods and Protocols promises to serve as a vital guide and resource for investigators and clinicians working toward the goal of combatting the estimated 2, 200 inflammation-related oncogenesis fatalities occurring every day.