Humana The Chemokine Receptors (The Receptors)

Product Description This volume, new to The Receptors series, focuses on several areas, including the birth, maturation, and structure of Chemokines; Neutrophil, Dendritic, and Lymphocyte trafficking; and Chemokine Receptors in diseases such as AIDs and lung cancer. In particular the book contains cutting-edge information ranging from basic molecular and cellular mechanisms to physiological and pathological roles of chemokines. Review From the reviews: "This book aims to report the knowledge concerning chemokines and their receptors in the context of human physiology, pathology, and future therapeutic possibilities. … this book gives an interesting analysis of the different fields of knowledge and research concerning chemokines and their receptors in recent years. In this way, this book remains interesting for less experienced and mature researchers … ." (Liliane Gattegno, ChemMedChem, Issue 3, 2008) "The Chemokine Receptors is an impressive and timely overview of the current knowledge in this field. The target readership includes researchers … clinicians including infectiologists, rheumatologists, oncologists and others may surely find information in this book, shedding light on their field of medicine. As such, the book can be used both by people entering the field and by more experienced researchers seeking new insights. … The volume contains numerous figures (including colour plates) as well as informative tables."(F. De Keyser, Acta Clinica Belgica, Vol. 63 (4), 2008) From the Back Cover To date, there are over twenty different chemokine receptors, binding nearly fifty unique ligands that have been identified. In Chemokine Receptors, leading investigators attempt to distill the large body of literature ranging from basic molecular and cellular mechanism of chemokine receptors, to physiological and pathological roles of chemokines. Chemokines exhibit a tremendous functional diversity and participate in a wide variety of processes that include inflammation, innate and adaptive immunity, immune cell differentiation, angiogenesis, tumorigenesis, development, neurobiology and viral pathogenesis. Chemokine Receptors targets the pharmaceutical industry, provides an authoritative perspective on the future direction of this field, and insights into areas of active development of novel therapeutics.