Humana Neuroprotection Methods and Protocols: 399 (Methods in Molecular Biology, 399)

This book examines current research into the role of neuronal death in cell signaling pathways, and its role in neurodegenerative diseases, such as Alzheimer's and Parkinson's. After introducing neurodegenerative, traumatic, and ishemic disorders, the authors cover in vitro and animal systems, and cellular and molecular mechanisms. Review From the reviews: "Research in neuroprotection is essential for the development of therapies for stroke and neurodegenerative diseases. This book reviews research methods currently used for prevention and slowing of central nervous system degenerative disorders. … Neurologists, neurosurgeons, and neuroscientists interested in research in neuroprotection are the main audience for this book. This is a comprehensive approach to research in neuroprotection. … the book is well written and structured with no drawbacks. ... a good book for neuroscience and neurological libraries." (Celso Agner, Doody’s Review Service, December, 2007) From the Back Cover Due to an aging population, the incidence of age-related neurodegenerative diseases is expected to rise dramatically.  In Neuroprotection Methods and Protocols, a team of skilled, renowned researchers provide step-by-step laboratory protocols intended to slow or prevent the progression of such diseases.  Focusing on neuroprotective approaches, this volume describes basic scientific discoveries and the application of such research within different laboratories in a clear and systematic way in order to orient scientists in this complicated field.  The chapters follow the Methods in Molecular Biology™ series format, consisting of readily reproducible methods, lists of the necessary materials, and a Notes section which aids the researcher in solving and avoiding technical problems. Comprehensive and easy to use, Neuroprotection Methods and Protocols is the perfect reference for basic neuroscientists hoping to move forward the ever-important field of neuroprotection and neuronal death research.