CRC Press Nanomedicines and Nanoproducts: Applications, Disposition, and Toxicology in the Human Body

Nanomedicines and Nanoproducts: Applications, Disposition, and Toxicology in the Human Body provides a detailed overview of the disposition of nanoproducts within the body, with a special focus on the respiratory and olfactory routes of nanoproduct administration, buccal exposure and the ingestion of nanoproducts, the integumentary system (formed by the skin, hair, nails, and associated glands), the ocular route, the systemic route, and toxicology as it relates to the nanoscale world. Offering an interdisciplinary, big-picture view of the current and future state of nanotechnology, this book: Identifies key points for the entry of nanoproducts, nanomedicines, and other nanoscale structures into the body Reviews the bodily administration and subsequent disposition of nanoproducts via various exposure routes Describes the intravenous route of administration for the therapeutic management of ocular disease Discusses practical nanoproduct and nanomedicine applications, disposition, and toxicology Summarizes various toxicological principles and the testing of nanoproducts Nanomedicines and Nanoproducts: Applications, Disposition, and Toxicology in the Human Body addresses the scope of practical nanoparticle applications in academic research as well as industrial investigation, where "practical" is defined as advantageous in all aspects of nanoproduct disposition, efficacy, and toxicology. The book’s goal is to introduce potentially beneficial applications and exciting topics regarding nanoproducts to a variety of professional and general readers. Review "… a comprehensive text for all nanoscientists … [that] deals extensively with nanoparticles ranging from organic (liposomes, micelles, and nanocrystals) to nondegradable organic (carbon nanotube) and inorganic (gold, silver, and titanium), and is very useful to understand widely the drug delivery systems of nanoparticles."―Kazuhiro Kagami, Activus Pharma Co., Ltd., Tokyo, Japan About the Author Eiki Igarashi is CEO of Nanosion Co., Ltd., a nanobioventure company in Tokyo, Japan. He is also a guest investigator at the National Institute of Advanced Industrial Science and Technology, Tokyo, Japan, where he collects and reviews medical information regarding the practical application, toxicology, and pharmacokinetics of nanoproducts and nanomaterials, ranging from metallic nanoparticles and carbon nanotubes to nanomedicines, nanofoods, nanocosmeceuticals, and nanoconsumer products. He holds a doctoral degree from Hiroshima University, Japan, and has worked in various capacities with Marion Merrell Dow Co., Ltd. (the pharmaceutical company of the Dow Chemical Company), Hirakata, Japan; Kyoto University, Japan; and Hoechst Marion Roussel Co., Ltd., Tokyo, Japan.