Humana TRP Channels in Drug Discovery: Volume I: 0 (Methods in Pharmacology and Toxicology)

With state-of-the-art reviews of the most interesting TRP channels, from TRPA1 to TRPV4, this volume contains key tips on implementation as well as clear and focused laboratory-ready protocols on TRP channels and disorders of airways and the GU tract. From the Back Cover Recent findings have implied a distinct therapeutic potential for drugs targeting Transient Receptor Potential (TRP) channels in a wide variety of diseases, many with no existing satisfactory treatment options. Thus, the TRP superfamily of ion channels has attracted a great deal of well-deserved attention.  TRP Channels in Drug Discovery provides a thorough collection of the most up-to-date reviews and protocols on the subject, coming from top experts in the field.  Volume I presents a series of state-of-the-art minireviews on the most interesting TRP channels (from TRPA1 to TRPV4), as well as TRP-related protocols involving airways and the genitourinary tract.  Written for the Methods in Pharmacology and Toxicology™ series, this work includes the kind of detailed description and key implementation advice that ensures successful results in the lab.  Comprehensive and cutting-edge, TRP Channels in Drug Discovery serves as an ideal reference for graduate students in academic laboratories as well as for pharmaceutical scientists developing new drugs and clinicians interested in novel drugs in the pipeline.