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Academic Press Role of TRPV4 Channels in Different Organ Systems: Volume 89 (Current Topics in Membranes, Volume 89)

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Description

TRPV4 Channels in Different Organ Systems, Volume 89, the latest release in the Current Topics in Membranes series, provides an in-depth description of the role of TRPV4 ion channels in different organ systems under healthy and disease conditions. Research over the last two decades shows crucial physiological and pathological roles for TRPV4 channels. In this volume, we present a collection of chapters focusing on TRPV4 ion channel properties, function, and regulation in multiple organ systems, including vasculature, brain, eye, lungs, heart, skeletal muscle, and urinary tract. Review Roles of TRPV4 channels in different organ systems About the Author Swapnil Sonkusare is an Associate Professor in Molecular Physiology and Biological Physics and a Resident Faculty in the Robert M. Berne Cardiovascular Research Center at the University of Virginia, Charlottesville. His research focuses on the regulation of blood flow and blood pressure by calcium signaling mechanisms in the vascular wall. He has investigated vascular calcium channels in health and disease throughout his scientific career. His main goals are to define the abnormalities in vascular calcium signaling mechanisms in cardiovascular disorders and to identify novel therapeutic targets. His laboratory routinely uses high-end calcium imaging, superresolution imaging, patch-clamp electrophysiology, vascular assays, mouse models of vascular disorders, and transgenic mice. Current NIH- and AHA-funded studies in my laboratory use this unique combination of techniques to address 1) new calcium signaling mechanisms that control vascular contractility and blood pressure in systemic and pulmonary vasculature; 2) contribution of impaired vascular calcium signaling and vascular inflammation to obesity-induced hypertension.

Product Specifications

Format
hardcover
Domain
Amazon UK
Release Date
23 September 2022
Listed Since
09 February 2022

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