Springer Molecular Pathology of Liver Diseases: 5 (Molecular Pathology Library, 5)

Product Description Cellular and Molecular Pathology of the Liver is extensive, complex and ranges from the understanding the basic molecular mechanisms that dictate everything from liver homeostasis to liver disease. Molecular Pathology of the liver is complicated due to some of the important functions inherent and unique to the Liver, including its innate ability to regenerate and the multitude of functions it plays for the wellbeing of an organism. With all this in mind, Molecular Pathology of Liver Diseases is organized in different sections, which will coherently and cohesively present the molecular basis of hepatic physiology and pathology. The first two sections are key to understanding the liver anatomy and physiology at a cellular level and go on to define the molecular mechanics in various liver cell types. These sections also cover the existing paradigms in liver development, regeneration and growth. The next section is key to understanding the Molecular Pathology unique to liver diseases and associated phenotypes. The final sections are geared towards the existing knowledge of the molecular basis of many common and uncommon liver diseases in both neoplastic and non-neoplastic areas including pathologies associated with intra-hepatic and extra-hepatic biliary tree. Thus, this textbook is a one-stop reference for comprehending the molecular mechanisms of hepatic pathobiology. It is clearly unique in its format, readability and information and thus will be an asset to many in the field of Pathology and other disciplines. From the Back Cover Molecular Pathology of Liver Diseases integrates the traditional knowledge of physiological and pathological processes in the liver with a balanced emphasis on fundamental concepts; timely advances in cellular and molecular mechanisms; and applied pathology. The textbook is organized into several sections, each of which includes an array of chapters that progressively and cohesively elaborate on pertinent liver biology and pathology. The first three sections discuss the cellular composition of the liver along with their specialized functions, and further dissect the molecular basis of the cellular processes that are so unique to the liver. The next section examines the mechanisms that are commonly implicated in the cellular and molecular basis of several hepatic pathologies, followed eventually by a section each on a multitude of non-neoplastic and neoplastic diseases of the liver. Molecular Pathology of Liver Diseases is a comprehensive reference on liver pathobiology for basic, translational and clinical researchers and physicians The format of the volume will serve as a ready reference to relevant topics in the liver, thus providing a practical disease-based integrative resource on the molecular pathology of liver disease. Satdarshan (Paul) Singh Monga, MD is Director: Division of Experimental Pathology and Associate Professor of Pathology and Medicine, University of Pittsburgh, Pittsburgh, PA About the Author Satdarshan (Paul) Singh Monga, M.D. is Director: the Division of Experimental Pathology and Associate Professor of Pathology and Medicine, University of Pittsburgh, Pittsburgh, PA