Gene Targeting Protocols: 133 (Methods in Molecular Biology, 133) - Image 1

£107.31

Humana Gene Targeting Protocols: 133 (Methods in Molecular Biology, 133)

Name: Gene Targeting Protocols: 133 (Methods in Molecular Biology, 133)
Brand: Humana
Price: 107.31 GBP
Availability: InStock

Laboratory Medicine

It has never been this cheap. We have no record of a lower price.

£107 today · cheaper than every other day in the last 3 months

NEW HERE?

Amazon shows you one price. We show you all of them.

Tosheroon watches Amazon prices so you don't have to. Every product on Amazon has a price history — we make it visible. Set the price you'd actually pay, and we'll email you the second it gets there. No app, no account, one email.

WHAT'S ON THIS PAGE

↓ Price chart
when this has been cheap or pricey

↓ Forecast
where the price is heading next

↓ Statistics
all-time high & low, recent range

↑ Price alert
name your number, we'll email you

Price History & Forecast

Grey patches = out of stock. Cheaper = lower on the chart. Hover for exact prices.

Last 55 days • 55 data points (No recent data available)

Historical

Generating forecast...

Price Distribution

Price distribution over 55 days • 1 price levels

Days at Price

Price Analysis

Most common price: £107 (55 days, 100.0%)

Price range: £107 - £107

Price levels: 1 different prices over 55 days

Description

The potential now exists in many experimental systems to transfer a cloned, modified gene back into the genome of the host organism. In the ideal situation, the cloned gene is returned to its homologous location in the genome and becomes inserted at the target locus. This process is a controlled means for the repair of DNA damage and ensures accurate chromosome disjunction during meiosis. The paradigm for thinking about the mechanism of this p- cess has emerged primarily from two sources: (1) The principles of reaction mechanics have come from detailed biochemical analyses of the RecA protein purified from Escherichia coli; and (2) the principles of information transfer have been derived from genetic studies carried out in bacteriophage and fungi. A compelling picture of the process of homologous pairing and DNA strand exchange has been influential in directing investigators interested in gene t- geting experiments. The ability to find and pair homologous DNA molecules enables ac- rate gene targeting and is the central phenomenon underlying genetic recombi- tion. Biochemically, the overall process can be thought of as a series of steps in a reaction pathway whereby DNA molecules are brought into homologous register, the four-stranded Holliday structure intermediate is formed, hete- duplex DNA is extended, and DNA strands are exchanged. Not much is known about the biochemical pathway leading to homologous recombination in euka- otes.

Product Specifications

Brand: Humana
Format: paperback
ASIN: 1489941584
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Allied Health Professions > Laboratory Medicine
Domain: Amazon UK
Publication Date: 14 August 2013
Listed Since: 06 August 2014

Barcode

No barcode data available

Humana Gene Targeting Protocols: 133 (Methods in Molecular Biology, 133)

It has never been this cheap. We have no record of a lower price.

Price History & Forecast

Price Distribution

Price Analysis

Description

Product Specifications

Barcode

Similar Products You Might Like

Molecular Genetics of Recombination: 17 (Topics in Current Genetics, 17)

DNA Recombination: Methods and Protocols: 745 (Methods in Molecular Biology, 745)

DNA Recombination: Methods and Protocols: 745 (Methods in Molecular Biology, 745)

Replicating And Repairing The Genome: From Basic Mechanisms To Modern Genetic Technologies

Homing Endonucleases: Methods and Protocols: 1123 (Methods in Molecular Biology)

Gene Cloning: The Mechanics of DNA Manipulation (Outline Studies in Biology)

Academic Press DNA Repair Enzymes Volume 592 - Methods in Enzymology

DNA Repair: 12 (Nucleic Acids and Molecular Biology, 12)

Synthetic DNA: Methods and Protocols: 1472 (Methods in Molecular Biology, 1472)

Springer - Site-directed insertion of transgenes (Vol. 23)

DNA Repair Enzymes: Cell, Molecular, and Chemical Biology (Volume 591) (Methods in Enzymology, Volume 591)

Advanced Molecular Genetics

Flipons: The Discovery of Z-DNA and Soft-Wired Genomes

Molecular Diagnosis and Gene Therapy: 88 (Falk Symposium, 88)

Homologous Recombination: Methods and Protocols: 2153 (Methods in Molecular Biology, 2153)

Humana Recombinant Gene Expression Protocols: 62 (Methods in MB)

Humana Recombinant Gene Expression Protocols: 62 Book

Gene Cloning and DNA Analysis: An Introduction

Replication of Viral and Cellular Genomes: Molecular events at the origins of replication and biosynthesis of viral and cellular genomes: 2 (Developments in Molecular Virology, 2)

Introduction to Genetics: A Molecular Approach

DNA Repair Protocols: Prokaryotic Systems: 152 (Methods in Molecular Biology, 152)

Handbook of Genetics: Volume 1 Bacteria, Bacteriophages, and Fungi

Genetic Recombination Research Progress

Academic Press - The DNA Replication-Repair Interface Vol 661