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Springer BetaSys: Systems Biology of Regulated Exocytosis in Pancreatic ß-Cells

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Description

BetaSys uses the example of regulated exocytosis in pancreatic β-cells, and its relevance to diabetes, to illustrate the major concepts of systems biology, its methods and applications. Review From the reviews:“This second volume is Springer’s Systems Biology series focuses on the organisation of pancreatic insulin-producing beta cells, with a particular focus on the technological approaches deemed necessary to further our understanding of beta cell physiology and the pathogenesis of diabetes. … I warmly recommend should be on the shelves of all research laboratories involved in modern beta cell research.” (P. Meda, Diabetologia, Vol. 54, 2011) From the Back Cover The insulin secreting β-cell is one of the most specialized cell types with diverse and multi-functional components (genes, gene products, organelles and metabolites) and a multitude of regulatory strategies in response to internal and environmental signals. This book looks at the technological advances that make simultaneous detection of thousands of biological variables possible; at a substantial variety of mathematical models and numerical simulations that aim to explain major aspects of the β-cell function; and at the challenge to formulate a comprehensive and robust model of the main networks of the underlying biochemical and physical processes for diagnostic and therapeutic use.

Product Specifications

Format
paperback
Domain
Amazon UK
Release Date
19 April 2013
Listed Since
04 April 2013

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