CRC Press Advances in Nutraceutical Applications in Cancer: Recent Research Trends and Clinical Applications: Recent Research Trends and Clinical Applications

Dietary supplements and nutraceuticals such as Vitamin A and D, Omega-3 and probiotics are used as part of the cancer treatment as complimenting the main therapy. Several Nutraceuticals have shown to boost the immune responses, while emerging clinical studies and other research suggests that some plant-based agents may, indeed, impact late-stage cancer, influencing molecular processes corrupted by tumor cells to evade detection, expand clonally, and invade surrounding tissues. Advances in Nutraceutical Applications in Cancer: Recent Research Trends and Clinical Applicationsis an attempt to collect evidence and related clinical information of application of Nutraceuticals to be used in cancer treatment or compliment the cancer treatment. It contains 16 chapters written by experts in related field’s and covers many different aspects of the formulation and development of Nutraceuticals for cancer applications. This book covers efficacy, safety and toxicological aspects of nutraceuticals. It also addresses various novel drug delivery systems of nutraceuticals with anticancer properties, as well as nutraceuticals as supplements for cancer prevention. Features:Offers a comprehensive view of neutraceuticals’ role in cancer prevention and treatmentCovers the applications and implications of neutraceuticals in prostate, colorectal, breast and gynecological cancersDiscusses the principles of neutrigenomics and neutrigenetics in cancer preventionExplors the role of probiotics and micronutrients in cancer treatment and preventionNutraceuticals can alter the gut microbiota. Gut microbiome undergoes changes during the disease status and followed by the cancer treatment. Nutraceutical’s role in proliferation and prevention of gynecological cancers, nutraceutical’s role in proliferation and prevention of prostate cancer and role of micronutrients in cancer prevention, both pros and cons, are some of the topics discussed in various chapters in this book. This book is addressed to scientists, clinicians, and students who are working in the area of Nutraceutical applications in cancer treatment. Review 'This book attempts to summarize the existing evidence regarding mechanisms of action and applications of a broad range of nutraceuticals either for chemoprophylaxis of solid tumors or as supplements to alleviate chemotherapy-induced toxicities. In addition, two chapters discuss delivery systems utilized for administration of nutraceuticals. One chapter is dedicated to discussion, although rather limited, of the Indian diet and its role in cancer prevention; this is a valuable and unique feature since India has the lowest incidence of cancers in comparison to the Americas, Africa, and China. 'The purpose [of this book] is to summarize the data on the role of nutraceuticals in cancer management. This is a highly noteworthy and ambitious goal. The results of multiple surveys, personal encounters, and experiences shared by healthcare practitioners reflect a tremendous public interest on the subject as well as consumption of the supplements in discussion. It is difficult to underestimate the usefulness of such a book for medical and allied health educational purposes.'-- Anna Dushenkov, Fairleigh Dickinson University About the Author Sheeba Varghese Gupta, MPharm, PhD, is an associate professor, Departmentof Pharmaceutical Sciences, College of Pharmacy, University of South Florida,Tampa, Florida. She received her PhD at Wayne State University, Michigan, andearned her MS in Pharmaceutical Chemistry from Bharati Vidhya Peeth PoonaCollege of Pharmacy, University of Pune, Maharashtra, India. Her research interestsare novel drug delivery systems, improving oral absorption of poorly absorbeddrugs, and patient outcomes. She has authored many peer-reviewed publications,book chapters and abstracts.Dr. Yashwant V. Pathak completed his PhD in Pharmaceutical Technology atNagpur University, India, and EMBA and MS in C