£82.99

Cold Spring Harbor Laboratory Press The p53 Family: A Subject Collection from Cold Spring Harbor Perspectives in Biology

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£82.99 £80.10 £80.73 £81.36 £81.99 £82.62 £83.25 09 March 2026 31 March 2026 22 April 2026 14 May 2026 06 June 2026

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Description

The p53 tumor suppressor gene the guardian of the genome protects cells against genotoxic stress but is mutated in many cancers. It encodes one of a family of transcription factors (p53, p63, and p73) that regulate cell proliferation, differentiation, senescence, and cell death. Mutations in p53 allow cells to escape normal growth controls and thereby contribute to tumor malignancy.

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