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Cold Spring Harbor Laboratory Press The p53 Family: A Subject Collection from Cold Spring Harbor Perspectives in Biology

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£85.00 £82.79 £83.27 £83.75 £84.24 £84.72 £85.20 07 June 2026 22 June 2026 08 July 2026 23 July 2026 08 August 2026

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Description

The p53 tumor suppressor gene the guardian of the genome protects cells against genotoxic stress but is mutated in many cancers. It encodes one of a family of transcription factors (p53, p63, and p73) that regulate cell proliferation, differentiation, senescence, and cell death. Mutations in p53 allow cells to escape normal growth controls and thereby contribute to tumor malignancy.

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