Cell Death: The Role of PARP (Handbooks in Pharmacology and Toxicology) - Image 1

£94.99

CRC Press Cell Death: The Role of PARP (Handbooks in Pharmacology and Toxicology)

Name: Cell Death: The Role of PARP (Handbooks in Pharmacology and Toxicology)
Brand: CRC Press
Price: 94.99 GBP
Availability: InStock

Pharmacology

It has never been this cheap. We have no record of a lower price.

£95 today · cheaper than every other day in the last 3 months

NEW HERE?

Amazon shows you one price. We show you all of them.

Tosheroon watches Amazon prices so you don't have to. Every product on Amazon has a price history — we make it visible. Set the price you'd actually pay, and we'll email you the second it gets there. No app, no account, one email.

WHAT'S ON THIS PAGE

↓ Price chart
when this has been cheap or pricey

↓ Forecast
where the price is heading next

↓ Statistics
all-time high & low, recent range

↑ Price alert
name your number, we'll email you

Price History & Forecast

Grey patches = out of stock. Cheaper = lower on the chart. Hover for exact prices.

Last 19 days • 19 data points (No recent data available)

Historical

Generating forecast...

Price Distribution

Price distribution over 19 days • 1 price levels

Days at Price

Price Analysis

Most common price: £95 (19 days, 100.0%)

Price range: £95 - £95

Price levels: 1 different prices over 19 days

Description

Poly (ADP-ribose) polymerase (PARP), also termed poly (ADP-ribose) synthetase (PARS) is a nuclear enzyme with a wide range of functions, including regulation of DNA repair, cell differentiation, and gene expression. More than a decade after the identification of PARP-like enzymatic activities in mammalian cells, a novel role was proposed for this enzyme, mediating a suicidal mechanism triggered by DNA strand breakage. This hypothesis has since become a controversial centerpiece of the PARP field, with many experimental systems both confirming and extending the PARP suicide theory. Theoretical and practical implications of the PARP suicide pathway were not extensively exploited until the 1990s. Researchers, for example, discovered a variety of findings; among them, that nitric oxide can activate a pathway leading to cell death (Neuronal cell death and pancreatic cell death), and that peroxynitrite, a reactive oxidant species produced from the reaction of nitric oxide and superoxide free radicals, is an endogenously produced trigger of DNA single strand breakage and PARP activation. Featuring contributions from researchers in the diverse fields of neuroinjury, myocardial injury, diabetes, shock, and inflammation, this text examines the current status of the field of PARP and cell death. Cell Death: The Role of PARP also explores PARP and apoptosis, PARP and DNA repair, as well as PARP and regulation of gene expression. Separate chapters focus on developments in the areas of pharmacological inhibition of PARP and on novel ways of measuring PARP activation. Furthermore, the emerging field of PARP isoforms is addressed. While tremendous progress has been made in the area of PARP and cell death, many controversies need to be clarified, and recent discoveries and observations require further development. Cell Death: The Role of PARP not only presents a state-of-the-art overview of the field, but serves as a catalyst for further research in this area.

Product Specifications

Brand: CRC Press
Format: hardcover
ASIN: 0849322677
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Other Branches of Medicine > Pharmacology
Domain: Amazon UK
Release Date: 22 June 2000
Listed Since: 10 February 2007

Barcode

No barcode data available

CRC Press Cell Death: The Role of PARP (Handbooks in Pharmacology and Toxicology)

It has never been this cheap. We have no record of a lower price.

Price History & Forecast

Price Distribution

Price Analysis

Description

Product Specifications

Barcode

Similar Products You Might Like

Cell Death: Mechanism and Disease

Wiley When Cells Die II - Apoptosis and Programmed Cell Death

Springer Apoptosis - Oxidative Stress and Ca2+ Homeostasis Book

Apoptosis and Its Modulation by Drugs: 142 (Handbook of Experimental Pharmacology, 142)

Apoptosis and Its Modulation by Drugs: 142 (Handbook of Experimental Pharmacology, 142)

Programmed Cell Death Part B: Pt. B (Methods in Enzymology): Volume 446

Programmed Cell Death

Cell Apoptosis: Regulation and Environmental Factors - Book

Programmed Cell Death: The Cellular and Molecular Biology of Apoptosis

Cell Apoptosis: Research Trends - Nova Science Publishers

Springer Apoptosis: Pezcoller Symposium Proceedings Vol. 5

Cell Apoptosis Research Advances

Cell Apoptotic Signaling Pathways

Apoptotic and Non-apoptotic Cell Death: 403 (Current Topics in Microbiology and Immunology, 403)

Apoptosis and Beyond, 2 Volume Set: The Many Ways Cells Die

Apoptosis and Cancer: Methods and Protocols: 414 (Methods in Molecular Biology, 414)

Apoptosis in Cardiac Biology: 5 (Basic Science for the Cardiologist, 5)

Apoptosis in Cardiac Biology: 5 (Basic Science for the Cardiologist, 5)

Nova Science - New Developments in Cell Apoptosis Research

Springer - Molecular Mechanisms of Programmed Cell Death

Mechanisms of Cell Death and Opportunities for Therapeutic Development (Perspectives in Translational Cell Biology)

Cellular Signaling and Apoptosis Research - Nova Science Publishers

Programmed Cell Death, Volume I: Cellular and Molecular Mechanisms (Volume 5) (Advances in Cell Aging and Gerontology, Volume 5)

Cell Apoptosis Research Progress