Wiley Clinical Cancer Genetics: Risk Counseling and Management

With a Foreword by Richard D. Klausner, M.D., Director, National Cancer Institute and an Introduction by Henry T. Lynch, M.D., President, Hereditary Cancer Institute and Director, Creighton Cancer Center, Creighton University. When ordering a genetic test to determine whether a patient is susceptible to genetically transmitted cancers, physicians must be prepared to cope with profound medical, psychological, and ethical consequences. They, along with genetic counselors, nurses, psychologists, and other health professionals, must ensure that interpretations of test results are accurate, risk assessments are appropriate, and the communication of risk information is clear, helpful, and productive. Clinical Cancer Genetics: Risk Counseling and Management is a comprehensive practical guide for health professionals responding to the growing demand for clinical cancer genetic services. Using examples drawn from actual cases and emphasizing fundamental principles throughout, this book outlines the scope of clinical cancer genetics and its underlying scientific concepts, reviews the most prevalent syndromes of cancer predisposition, and addresses major issues associated with genetic testing, including: * Use of quantitative methods in risk counseling * Methodologies of genetic testing * Genetic testing of patients with cancer * Reproductive risk counseling of cancer patients * Special psychological, ethical, and legal challenges in clinical cancer genetics Supplemented with practical materials used in cancer genetic counseling programs and an annotated table of selected human cancer predisposition syndromes, Clinical Cancer Genetics: Risk Counseling and Management equips health care professionals with a complete understanding of the benefits and limitations of genetic testing technologies and the ability to integrate genetic information into the management of patients who are at risk or already affected by cancer. Review "I refer to [this book] frequently and almost feel as if Dr. Offit was in the consulting room. I urge oncologists and other professionals providing cancer risk counseling to read this book and keep it at hand for convenient reference." --Annals of Oncology "This is an excellent textbook ...it will be on my list of recommended reading for students...." (Human Genetics, May 2000) "This is an excellent textbook encompassing a wealth of experience." (Human Genetics, No. 106, 2000) From the Publisher These are reviews which have appeared for Clinical Cancer Ge "Dr. Offit's book on cancer genetics in clinical practice covers most of the essential material in this complex field in a highly effective and readable way. The role of genetics in cancer is put into context by a superb overview of the role of genetics in disease, and Offit reviews our current knowledge of specific forms of genetic predisposition in both common and rare cancers. Using this information, he is able to discuss the difficult aspects of applying this knowledge in the clinic, providing case histories to help illustrate problems." -- New England Journal of Medicine From the Inside Flap With a Foreword by Richard D. Klausner, M.D., Director, National Cancer Institute and an Introduction by Henry T. Lynch, M.D., President, Hereditary Cancer Institute and Director, Creighton Cancer Center, Creighton University. When ordering a genetic test to determine whether a patient is susceptible to genetically transmitted cancers, physicians must be prepared to cope with profound medical, psychological, and ethical consequences. They, along with genetic counselors, nurses, psychologists, and other health professionals, must ensure that interpretations of test results are accurate, risk assessments are appropriate, and the communication of risk information is clear, helpful, and productive. Clinical Cancer Genetics: Risk Counseling and Management is a comprehensive practical guide for health professionals responding to th