Elsevier Analysis of Marine Samples in Search of Bioactive Compounds (Comprehensive Analytical Chemistry): Volume 65

Seas and oceans offer a wide range of temperature, pressure, light and chemical conditions thus allowing a wide diversity of marine organisms from shallow coastal waters to the deep ocean. These resources can be used to obtain new products and develop services, and in turn help to provide solutions to the challenges that affect our planet, including offering a sustainable supply of food and energy, new industrial materials and processes, new bioactive compounds, and new health treatments. Marine compounds have been identified as having antibacterial, anticoagulant, antifungal, antimalarial, antiprotozoal, antituberculosis, and antiviral activities. The major sources of these bioactive compounds are marine sponges, coelenterates, and microorganisms, followed by algae, echinoderms, tunicates, molluscs, and bryozoans. The discovery of bioactive compounds from marine samples is a hot topic considering the current need for sustainable use of marine resources. This book is a comprehensive overview of the analytical techniques employed in the discovery and characterization of bioactive compounds isolated from (all possible) marine samples and gives future perspectives of analytical methodologies. This overview includes an assessment of the sampling and preparation of extracts, the separation and isolation of bioactive compounds, their structural characterization and the application of bioassays in the discovery of bioactive compounds. * Comprehensive coverage of analytical techniques and applications* Clear diagrams to adequately support important topics* Real examples of applications of analytical techniques in the search for new bioactive compounds Review Highlighting analytical strategies for extraction, isolation and characterization of bioactive compounds from marine sources About the Author Dr. Teresa Rocha-Santos graduated in Analytical Chemistry (1996) and obtained a PhD in Chemistry (2000), both at the University of Aveiro, Portugal. In 2001 she was awarded a prize for her PhD studies in the area of the urban environment. She was an Assistant Professor at Instituto Piaget from 2000 to 2009. During this period she was the coordinator of the environmental chemistry graduation course (5 year degree) at Instituto Piaget. Currently, she is an Associate Professor at Instituto Piaget (from May 2009) and an integrated member at CESAM-University of Aveiro. Her research concentrates on the development of new analytical methodologies fit for purpose. She has published more than 80 peer-reviewed publications based on her research. Her work has been published in, among others, Trends in Analytical Chemistry, Science of the Total Environment, Journal of Hazardous Materials, Food Chemistry and Talanta. Prof. Armando C. Duarte (http://www.cesam.ua.pt/aduarte) graduated in Chemical Engineering (1977) at the University of Oporto (Portugal) and obtained a PhD in Public Health Engineering (1981) at the University of Newcastle-upon-Tyne (United Kingdom). In 2006, The Portuguese Science Foundation (www.fct.pt) awarded him a prize for Scientific Excellence and in 2013 he became a Member of the FCT Scientific Council for Natural and Environmental Sciences. He is a Professor of Environmental & Analytical Chemistry at the University of Aveiro (Portugal) since 1995, leader of a research group on the same subject, lecturer on Anaytical Quality Control subjects, and either supervising or co-supervising many PhD students, some of whom became members of staff, both as lecturers and researchers. His highly-interdisciplinary research spans areas of comprehensive environmental and analytical chemistry, qualimetrics and analytical quality assurance, but also includes the assessment of the relevance of new concepts and integration of different ideas into widely accepted frameworks, especially when applied to sustainability. He has collaborated in more than 350 peer-reviewed research papers leading to an h-factor of 30.