Academic Press Advances in Structural Biology: Applications in Protein Structure, Function, and Disease

Advances in Structural Biology: Applications in Protein Structure, Function, and Disease offers a comprehensive, practical resource that bridges the latest experimental and computational approaches in structural biology. Backed by real-world case studies, it demonstrates how these technologies can be utilized to serve a range of biological needs. The content spans foundational principles of protein structure and bioinformatics tools, cutting-edge methodologies such as MicroED and Cryo-EM, and the transformative role of artificial intelligence and big data analytics in structural biology. It also considers applications including drug discovery, vaccine development, antiviral therapy, personalized medicine, and the structural basis of aging and neurodegenerative diseases. The book also explores systems integration approaches, combining structural and omics data to advance immunotherapy and cancer treatment, concluding with a look towards future trends in the field. Advances in Structural Biology provides a detailed investigation into the latest developments in structural and computational biology, sharing insights into integrative methodologies that combine both traditional and emerging technologies. This resource is invaluable for advanced students, researchers, and professionals aiming to harness structural biology for innovative solutions in precision medicine and translational research. • Provides a practical approach to explore systems biology and computational techniques • Examines the integration of molecular dynamics with omics data for deeper biological insights • Demonstrates applications of structural biology for drug design and the treatment of various diseases • Highlights advanced network analysis and AI applications in structural biology • Offers real-world examples of docking, pharmacophore modeling, and molecular simulations