Academic Press Structural Biology of Ubiquitination: From Mechanisms to Interventions

Structural Biology of Ubiquitination: From Mechanisms to Interventions provides an in-depth exploration of the structural and biophysical principles governing ubiquitination and their implications in diseases such as cancer and neurodegeneration. The book seamlessly integrates experimental insights with advanced computational methods, including AI-driven drug discovery, molecular modeling, and biophysical simulations, offering a comprehensive toolkit for researchers and clinicians. By bridging fundamental science with translational applications, the book empowers readers to design targeted therapeutics, understand disease mechanisms at the molecular level, and accelerate progress toward personalized medicine. Provides structural insights into ubiquitination pathways and their roles in diseases such as cancer and neurodegeneration Utilizes computational and AI-driven approaches to advance drug discovery Highlights the therapeutic relevance of the ubiquitin-proteasome system Bridges experimental and computational research to support precision medicine