Price loading...

The Physics of Protein Structure and Dynamics: When and Why Proteins Fold or Don’t Fold

Biological Science

Price data last checked 101 day(s) ago - refreshing...

View at Amazon

Price History & Forecast

No Price Data Available

Price history will appear here once data is collected from Amazon.

Price Distribution

No price data available for histogram

Description

The Physics of Protein Structure and Dynamics looks at various aspects of protein structure and dynamics from a physico-chemical point of view. It goes into some depth regarding the description of non-covalent forces that determine the relative stability of folded and unfolded proteins. Anharmonic protein dynamics involving motions between different minima of a rugged Gibbs energy landscape is described in great detail. The book combines various aspects of the protein folding/unfolding processes with an overview of intrinsically disordered proteins, which have attracted considerable interest of the protein community over the last 25 years but are thus far underrepresented in classroom-oriented textbooks. The book looks at protein folding and intrinsically disordered proteins as heavily interrelated topics that need to be viewed together. Furthermore, it presents some basic physico-chemical aspects of protein/peptide self-assembly into nanoscale fibrils. Intrinsically disordered peptides and proteins play a major role particularly in aggregation and self-assembly processes that lead to various diseases (Alzheimer, Parkinson, Huntington, Mad-Cow). Therefore, the relevance of protein disorder for protein self-assembly deserves a closer look. Protein self-assembly cannot be separated from protein folding since it is frequently the product of misfolding. With regard to modern theories, the folding processes are linked to insights on protein dynamics and the discovered relationship between proteins and spin glasses. The readers will benefit from being provided with an in-depth overview of the physical concepts that govern different aspects of protein folding, disorder and self-assembly. By emphasizing the relationship between these issues, the approach adds a holistic character to the book The book is to a major extent mathematically based. Mathematics is part of the language of physicists and physical chemists which cannot be properly substituted by words For instructors, the book will offer a unique source for her/his teaching of current protein physics issues The way how the book will be constructed (multiple references to primary literature with DOI links, literature-based problem sets and topics for discussion) will facilitate a learning process suitable for research-oriented students Problem solving frequently requires the writing of short computer programs, something that is underemphasized in chemistry and biochemistry education (with the exception of computationally trained students, of course)

Product Specifications

Format: paperback
ASIN: 0443159645
Category: Books > Subjects > Science, Nature & Maths > Biological Sciences > Biological Science
Domain: Amazon UK
Release Date: 30 September 2024
Listed Since: 24 January 2024

Barcode

No barcode data available

The Physics of Protein Structure and Dynamics: When and Why Proteins Fold or Don’t Fold

Price History & Forecast

No Price Data Available

Price Distribution

Description

Product Specifications

Barcode

Similar Products You Might Like

Protein Physics: A Course of Lectures (Soft Condensed Matter, Complex Fluids and Biomaterials)

Computational Approaches to Protein Dynamics: From Quantum to Coarse-Grained Methods (Series in Computational Biophysics)

Springer - Frontiers in Protein Structure, Function, and Dynamics

Springer - Physical Biology of Proteins and Peptides Book

Functionally Relevant Macromolecular Interactions of Disordered Proteins

Theory of Phase Transitions in Polypeptides and Proteins (Springer Theses)

Unfolded Proteins: From Denatured to Intrinsically Disordered

Springer Protein Conformational Dynamics: 805 - Biology Book

Bio-Nanoimaging: Protein Misfolding & Aggregation

Intrinsically Disordered Proteins (Volume 611) (Methods in Enzymology, Volume 611)

Humana Protein Misfolding and Disease: 232 Methods in Molecular Biology

Structure and Function of Intrinsically Disordered Proteins

The Three Functional States of Proteins: Structured, Intrinsically Disordered, and Phase Separated

Theory of Phase Transitions in Polypeptides and Proteins (Springer Theses)

Protein Folding Disorders Of The Central Nervous System

Statistical Physics of Biomolecules: An Introduction

Academic Press Dancing Protein Clouds - Volume 166

Introduction to Proteins: Structure, Function, and Motion, Second Edition (Chapman & Hall/CRC Computational Biology Series)

The Protein Folding Problem

Academic Press Dancing Protein Clouds Volume 174 - Part B

Single-molecule Studies of Proteins: 2 (Biophysics for the Life Sciences, 2)

Springer Introduction to Biomolecular Structure and Biophysics

Comprehensive Biophysics

Wiley Applied Biophysics: A Molecular Approach for Scientists