CRC Press Biomaterials

For medical devices that must be placed inside the body, the right choice of material is the most important aspect of design. To ensure such devices are safe, reliable, economical, and biologically and physiologically compatible, the modern biomedical engineer must have a broad knowledge of currently available materials and the properties that affect their in-service performance. In chapters drawn from the third edition of the best-selling , Biomaterials surveys the wide variety of biomaterials in present use as well as materials resulting from novel micro- and nanoscale technologies. The book includes a general overview of bioinert, bioactive or surface reactive ceramics, and biodegradable or re-absorbable bioceramics. It reviews basic chemical and physical properties of the synthetic polymers, covers the sterilization of the polymeric biomaterials, discusses the importance of the surface treatment for improving biocompatibility, and examines the application of the chemogradient surface for the study on cell polymer interactions. The book also provides an overview of the chemistry design, fabrication, and application of biodegradable hydrogels for drug delivery and tissue engineering. It explores current issues involved in probing cell-biomaterials interactions on the molecular level and their implications for tissue engineering research and examines advances in biodegradable polymeric materials, soft and hard tissue replacements, and applications in tissue engineering. Taking a focuses look at the latest advances in biomaterials, the book discusses metallic, ceramic, polymeric, and composite biomaterials. With more than 100 figures and tables, as well as contributions from a panel of international experts, the book gives you familiarity with the uses of biomaterials in medicine and dentistry About the Author Dr. Joyce Y. Wong is a Clare Boothe Luce associate professor in biomedical engineering (BME) and associate chair of graduate studies in the department of biomedical engineering at Boston University. Dr.Wong’s research focuses on the development of biomaterials to probe how structure, material properties and composition of the cell-biomaterial interface affect fundamental cellular processes. Her current research interests include tissue engineering of small diameter blood vessels for bypass and intravascular pharmacology (e.g. stents); development of targeted nano- and micro-particle contrast agents for multimodal (magnetic resonance, ultrasound, and optical) detection of atherosclerotic and vulnerable plaque; and engineering biomimetic systems to study restenosis and breast cancer. Awards she has received include a NSF Career Award and Dupont Young Professor Award. Dr. Wong is currently the associate director of the Center for Nanoscience and Nanobiotechnology at Boston University. She has served on NIH Study Section panels, and is on the editorial advisory board of the journal Polymer Reviews and co-editor of Biointerphases. She is also an active member of the American Chemical Society, Biomedical Engineering Society, Materials Research Society, AVS Science and Technology (executive committee member, Biomaterials Interfaces Division), Biophysical Society, Society for Biomaterials, and American Society of Cell Biology. Joseph D. Bronzino received the B.S.E.E. degree from Worcester Polytechnic Institute, Worcester, MA, in 1959, the M.S.E.E. degree from the Naval Postgraduate School, Monterey, CA, in 1961, and the Ph.D. degree in electrical engineering from Worcester Polytechnic Institute in 1968. He is presently the Vernon Roosa Professor of Applied Science, an endowed chair at Trinity College, Hartford, CT and President of the Biomedical Engineering Alliance and Consortium (BEACON), which is a nonprofit organization consisting of academic and medical institutions as