Academic Press Targeted Cancer Imaging: Design and Synthesis of Nanoplatforms based on Tumor Biology

Targeted Cancer Imaging: Design and Synthesis of Nanoplatforms based on Tumour Biology reviews and categorizes imaging and targeting approaches according to cancer type, highlighting new and safe approaches that involve membrane-coated nanoparticles, tumor cell-derived extracellular vesicles, circulating tumor cells, cell-free DNAs, and cancer stem cells, all with the goal of pointing the way to developing precise targeting and multifunctional nanotechnology-based imaging probes in the future. This book is highly multidisciplinary, bridging the knowledge gap between tumor biology, nanotechnology, and diagnostic imaging, and thus making it suitable for researchers ranging from oncology to bioengineering. Although considerable efforts have been conducted to diagnose, improve and treat cancer in the past few decades, existing therapeutic options are insufficient, as mortality and morbidity rates remain high. One of the best hopes for substantial improvement lies in early detection. Recent advances in nanotechnology are expected to increase our current understanding of tumor biology, allowing nanomaterials to be used for targeting and imaging both in vitro and in vivo experimental models. Review Presents new and safe approaches to targeted cancer imaging using nanoplatforms From the Back Cover <p>Although considerable efforts have been conducted to diagnose, improve, and treat cancer in the past few decades, existing therapeutic options are insufficient, as mortality and morbidity rates remain high. One of the best hopes for substantial improvement lies in early detection. Recent advances in nanotechnology are expected to increase our current understanding of tumour biology, and will allow nanomaterials to be used for targeting and imaging both in vitro and in vivo experimental models. Owing to their intrinsic physicochemical characteristics, nanostructures (NS) are valuable tools that have received much attention in nanoimaging. Consequently, rationally designed NS have been successfully employed in cancer imaging for targeting cancer-specific or cancer-associated molecules and pathways. </p> <p><i>Targeted Cancer Imaging: Design and Synthesis of Nanoplatofrms based on Tumour Biology</i> reviews and categorizes imaging and targeting approaches according to cancer type - highlighting some new and safe approaches that involve membrane-coated nanoparticles, tumour cell-derived extracellular vesicles, circulating tumour cells, cell-free DNAs, and cancer stem cells - with the goal of pointing the way to developing precise targeting and multifunctional nanotechnology-based imaging probes in the future. </p> <p>This book is highly multidisciplinary, bridging the knowledge gap between tumour biology, nanotechnology, and diagnostic imaging, making it suitable for researchers ranging from oncology to bioengineering.</p> About the Author Mehdi Azizi obtained his B.Sc. (Chemistry) from Razi University, Iran in 2012, and M.Sc. (Medical Nanotechnology) from Tehran University of Medical Sciences, Iran in 2016. He is currently a Ph.D. candidate in the Medical Nanotechnology department at Tabriz University of Medical Sciences, and working with Dr. Mohammad Mehrmohammadi group at biomedical imaging department of Wayne state University. His current research include synthesis, development and application of smart theranostic nanoplatforms.Mehdi Azizi obtained his B.Sc. (Chemistry) from Razi University, Iran in 2012, and M.Sc. (Medical Nanotechnology) from Tehran University of Medical Sciences, Iran in 2016. He is currently a Ph.D. candidate in the Medical Nanotechnology department at Tabriz University of Medical Sciences, and working with Dr. Mohammad Mehrmohammadi group at biomedical imaging department of Wayne state University. His current research include synthesis, development and application of smart theranostic nanoplatforms. Hadi Kokabi graduated in 2013 from Hamadan University S