Academic Press Computational Approaches for Novel Therapeutic and Diagnostic Designing to Mitigate SARS-CoV2 Infection: Revolutionary Strategies to Combat Pandemics

Computational Approaches for Novel Therapeutic and Diagnostic Designing to Mitigate SARS-CoV2 Infection: Revolutionary Strategies to Combat Pandemics compiles information about various computational bioinformatic approaches that can help combat viral infection. The book includes working knowledge of various molecular docking and molecular dynamic simulation approaches that have been exploited for drug repurposing and drug designing purpose. In addition, it sheds light on reverse vaccinomics and immunoinformatic approaches for vaccine designing against SARS-CoV2 infection. This book is an essential resource for researchers, bioinformaticians, computational biologists, computational chemists and pharmaceutical companies who are working on the development of effective and specific therapeutic interventions and point-of-care diagnostic devices using various computational approaches. Review A comprehensive overview of computational approaches exploited for drug designing, screening and repurposing About the Author Dr. Arpana Parihar is currently working as a Women Scientist B at CSIR-Advanced Materials and Processes Research Institute (AMPRI), Bhopal, MP, India, under the scheme of DST-WoS-B awarded from Department of Science and Technology, Government of India. She did her PhD from Raja Rammana Centre for Advanced Technology, Indore under the ages of HBNI, Mumbai. Her doctoral research work involves the evaluation of tumor selectivity and photodynamic therapy (PDT) efficacy of Chlorin p6 through receptor-mediated targeted delivery. After her PhD, she worked as a post-doctoral researcher at CBME, IIT Delhi. At IITD her research work was to enhance the osteoinductive and osteoconductive properties of various implants made up of metals, ceramic, and polymers. Dr. Parihar has been awarded GATE, CSIR-NET, DST-WoS A, and WoS B fellowship. She has more than 7 years of research and teaching experience at various prestigious institutes. Her current research interest includes -fabrication of biosensors for early diagnosis of cancer, viral Infection, Stem cell Biology, Tissue engineering, Photodynamic therapy of cancer, Receptor-mediated targeting of tumor, Biosensors for early diagnosis of diseases, 3D cell culture, Expression of receptors, and cytokine, Molecular docking, Molecular dynamic simulations, Immunoinformatics, Codon usage bias. At present, she published 3 books in Elsevier and wrote several book chapters in esteemed publishers such as Springer, Elsevier, Taylor and Francis, etc. Her research work gained considerable attention in various international journals and conferences. Dr. Khan is currently working as Principal Scientist at Microfluidics & MEMS Centre, CSIR-Advanced Materials and Processes Research Institute (AMPRI), Bhopal - 462026, MP, India. His current research on Bio-molecular separation, including sample preparation and detection, Microchip based separation under the concept of lab-on-a-chip and electrochemical biosensor integrated with microfluidics clinical applications. He has more than 15 years of R&D experience in CSIR & other academics R&D Institutes such as in Analytical Chemistry Group, CSIR-NEIST, Jorhat, Assam, CSIR-NPL, New Delhi and CSIR-AMPRI, Bhopal Govt. of India, respectively. He received his MSc degree in Inorganic Chemistry and Ph.D. in Physical Chemistry from Jamia Millia Islamia, Central University, New Delhi, India, in 2002 & 2005, respectively. After that, he worked as a Postdoctoral Fellow at the “Sensor Research laboratory Department of Chemistry, University of the Western Cape, Cape Town, South Africa, in the year 2005-06 and also worked as a Fast-Track Young Scientist at CSIR-National Physical Laboratory, New Delhi Govt. of India. Dr. Khan is involved in synthesizing novel materials to fabricate electrochemical biosensors to detect target disease risk biomarker for health care monitoring. Dr. Khan is also engaged in other external project