Academic Press The Vasculome: From Many, One

The Vasculome: From Many, One introduces the fundamental bases of the “unity in diversity of the Vasculome, from the coming together of various cell lineages during development, to its deceptively simple solution for architectural design: the efficient interplay of a few types of building blocks supporting key similar functions throughout the body and their highly specialized functional local variations. Specific examples are included to illustrate how the Vasculome is integral to the function and malfunction of different organs, such as the brain or the kidney. Each section is preceded by an introductory summary that will give a high level unified view of the key concepts illustrated in the various chapters in that section. Review Introduces readers to the integrative perspective of the Vasculome concept: one from many, integrated in itself and with the human body From the Back Cover <i>The Vasculome: From Many, One </i>highlights the unique integrative nature of the body-wide distributed vascular system. The book introduces the fundamental bases of the “unity in diversity of the Vasculome, from the coming together of various cell lineages during development, to its deceptively simple solution for architectural design: the efficient interplay of a few types of building blocks supporting key similar functions throughout the body and their highly specialized functional local variations. Specific examples are included to illustrate how the Vasculome is integral to the function and malfunction of different organs, such as the brain or the kidney. Each section is preceded by an introductory summary that will give a high level unified view of the key concepts illustrated in the various chapters in that section. Recognized experts are invited to contribute to this shared perspective of the Vasculome: from classic names and other outstanding researchers challenging the boundaries of fundamental understanding, to academic physicians ready to translate the latest scientific and technological advancements to holistically assess the contribution of the Vasculome to human health and disease, with the ultimate goal to improve prevention and treatment of a wide variety of medical conditions, and combining traditional and state of the art knowledge presented in a novel way. About the Author Dr. Zorina Galis has been a life-long vascular researcher, recognized thought leader, innovator, highly cited researcher, mentor, and a popular science educator. She was educated in physics, biophysics, cell biology, pathology, and vascular medicine at the University of Bucharest, Romania, the McGill School of Medicine, Montreal, Canada, and the Harvard School of Medicine, Boston, USA. A prominent feature of Dr. Galis’ career has been to capitalize on her own transdisciplinary training and experience to identify and pursue major scientific and implementation challenges requiring a diversity of expertise. She has created, mentored, and led such teams, first, in academic medicine, as a tenured professor of Medicine/Cardiology and Biomedical Engineering at Emory School of Medicine and the Georgia Institute of Technology, then, as a Cardiovascular pharmaceutical industry executive at Eli Lilly and Company, and, currently, at the National Institutes of Health (NIH). Her best known research works are related to pioneering hypotheses about the molecular bases of acute cardiovascular conditions, which have led to the development of new diagnostic and therapeutic interventions (Google Scholar) https://scholar.google.com/citations?user=Qwwqn60AAAAJ&hl=en Since joining the in 2011 as the Chief of the Vascular Biology and Hypertension Branch in the National Heart Lung and Blood Institute (NHLBI), Dr. Galis has continued to create and lead wide partnerships dedicated to enhancing fundamental vascular knowledge and its translation, including the Trans-NIH Small Blood Vessels in Health and Disease and th