Academic Press Textbook of Arterial Stiffness and Pulsatile Hemodynamics in Health and Disease

Textbook of Arterial Stiffness and Pulsatile Hemodynamics in Health and Disease, Two Volume Set covers the principles, physiology, biologic pathways, clinical implications and therapeutics surrounding arterial stiffness and pulsatile hemodynamics, along with a thorough overview of the field. The book presents complex engineering concepts in a way that those in science and medicine can more easily understand. It includes detailed illustrations, animations and slideshows. Additionally, it presents advanced bioengineering concepts in boxes for readers who wants more in-depth biophysical knowledge. This is a must-have reference for students, researchers and clinicians interested in learning more about this field. Review Provides a comprehensive review of the role of arterial stiffness and pulsatile hemodynamics in health and human disease From the Back Cover <p>Most biology-oriented books misinterpret the physiology of arterial stiffness and pulsatile arterial hemodynamics based on physics. A proper understanding of the field requires both biologic/clinical and biophysical/bioengineering knowledge which <i>Textbook of Arterial Stiffness and Pulsatile Hemodynamics in Health and Disease</i> provides in a comprehensive yet simplified manner. The resource is organized into five parts covering principles, physiology, biologic pathways, clinical implications and therapeutics and provides a thorough overview of the field, presenting complex engineering concepts in a way that those in science and medicine can more easily understand. </p> <i> <p>Textbook of Arterial Stiffness and Pulsatile Hemodynamics in Health and Disease</p></i><p> includes detailed illustrations, animations and slide shows. Additionally, advanced bioengineering concepts presented in boxes for the reader who wants more in-depth biophysical knowledge. This is a must-have reference for students, researchers and clinicians interested in learning more about this field. </p> About the Author Dr. Julio A. Chirinos, MD, PhD, is an Associate Professor of Medicine and Director of the Arterial Hemodynamics and Cardiac Imaging Quantification Core Laboratory at the University of Pennsylvania Perelman School of Medicine. Dr. Chirinos directs an NIH-funded research program focused on the role of arterial stiffness and ventricular arterial interactions in heart disease, mechanisms of human heart failure and the use of proteomics to discern mechanisms of human heart failure. He currently leads clinical studies and trials designed to therapeutically target the arterial tree in order to reduce maladaptive cardiac remodeling, diastolic dysfunction, and to treat patients with Heart Failure and Preserved Ejection Fraction, an epidemic condition for which no effective proven pharmacologic therapies are currently available. He also leads various cohort studies with deep cardiovascular phenotyping aimed at characterizing phenotypic profiles in humans. Dr. Chirinos also directs a core analysis laboratory for assessments of cardiac and arterial structure and function with non-invasive imaging, which has served as the core lab for various multicenter studies. His laboratory utilizes a combination of imaging modalities (including arterial tonometry, echocardiography and cardiac MRI) coupled with modeling approaches to characterize arterial physiology and ventricular-arterial interactions in humans. Dr. Chirinos has published >200 papers, chapters, reviews, and editorials and has been an invited speaker in >120 scientific sessions. He has participated in various clinical expert committees for the American Heart Association, American Society of Echocardiography, European Society of Cardiology, American Society of Hypertension, European Association of Cardiovascular Imaging and the Lancet Commission for Hypertension. Dr. Chirinos is currently the Vice-President of the North American Artery society, which promotes the study of arterial func