Academic Press Thermal Ablation Therapy: Theory and Simulation

Thermal Ablation Therapy: Theory and Simulation includes detailed theoretical and technical concepts of thermal ablation therapy in different body organs. Concepts of ablation technology based on different thermal ablation methods are introduced, along with changes in the tissues’ mechanical properties due to thermal denaturation. The book emphasizes the mathematical and engineering concepts of RF and MW energy propagation through tissues and where high heating rates produced by MW systems can overcome the heat-sink effects from nearby vessels. The design and tuning of the MW antennas to deliver energy efficiently to specific organ systems such as the liver or lung is also covered. Other sections cover the computational modeling of radiofrequency ablation and microwave ablation procedures for developing and implementing new efficient ablation in clinical systems, numerical simulations for different scenarios of different organs with different size using RF and MW ablation systems with different antennas’/probes design and configurations, and numerical techniques for temperature profile in tissues. Review Examines advances in thermal ablation therapy with mathematical models and simulation scenarios for various organs, including MATLAB and Comsol software From the Back Cover Thermal Ablation Therapy: Theory and Simulation includes detailed theoretical and technical concepts of thermal ablation therapy in the different body organs. The concepts of ablation technology based on the different thermal ablation methods are introduced in the book. Since the radiation pattern and the effect of the heat/cooling depends on the characteristics of the tissues and the size of the tumor, the book studies these factors using different energy sources. The changes in the tissues’ mechanical properties due to the thermal denaturation are also discussed. The book emphasizes the mathematical and engineering concepts of the RF and MW energy propagation through the tissues and the heating effect, where the high heating rate produced by the MW systems can overcome the heat-sink effects from nearby vessels, creating more uniform ablation zones. The design and tuning of the MW antennas to deliver energy efficiently to specific organ systems, such as the liver or lung is also studied in this book. The computational modeling of the radiofrequency ablation and the microwave ablation procedures for developing and implementing new efficient ablation in clinical systems is one of the main contents of this book. Numerical simulations for different scenarios of different organs with different size using RF and MW ablation systems with different antennas’/probes design and configurations are extensively included in this book. Numerical techniques for the temperature profile in tissue include the finite integration technique (FIT), finite element method (FEM), finite–difference time-domain (FDTD) and method of moments (MoM). These methods are widely used to discretize the partial differential equations (PDEs) in space and time. Such simulation will be performed in this book by using Matlab software by building finite element models or Comsol software, which is mainly concerned with building physical models to examine the thermal effect of the different antennas design on the tumor tissues and their neighbor normal tissues. COMSOL Multiphysics software is fortified with FEM to provide the required tools to build simulation applications relating to biological materials, physics components selection (electromagnetic and heat transfer), antenna geometry, and meshing. This is efficient to predict the electromagnetic waves propagation from the antennas of arbitrary geometry and to evaluate the antenna performance metrics. Thermal Ablation Therapy: Theory and Simulation also covers energy deposition from the applied electromagnetic fields, and heat generation as well as the subsequent water and vapor mass transfer in t