Wiley Stem Cell Therapeutics for Cancer

Stem Cell Therapeutics for Cancer covers the application of stem cells in various cancers, with an emphasis on the aspects of these strategies that are critical to the success of future stem cell-based therapies for cancer. Topics covered in the book include stem cell sources, tumor specificity, targeted therapeutics, visualizing the stem cell, and therapeutic agent pharmacokinetics. Each chapter contains a brief introduction to the cancer, followed by an exploration of how engineered stem cells have been utilized to cure the disease in mouse models and in early phase clinical trials. Comprises of sections on stem cell therapy in brain cancers, lung cancers, breast cancers, as well as stem cells in combination with other therapiesFocuses on the practical applications of using stem cells as gene delivery agents to treat cancerIncludes coverage of cutting-edge molecular imaging techniques in stem cell therapeutics for a variety of tumour types  From the Inside Flap A single-source reference on the hot topic of stem cell therapeutics for cancerThis work offers a thorough, cohesive look at the state of the art of stem cell therapeutics for cancer, with an emphasis on the unique application of mesenchymal stem cells (MSC) and MSC-like cells as gene-delivery agents in cancer treatment. Edited by a leader in the field, the book brings together a wealth of information from this growing area of research, highlighting topics critical to the success of future therapies, including stem cell sources, tumor specificity, targeted therapeutics, visualizing the stem cell, and therapeutic agent pharmacokinetics.Organized in sections according to disease types, the chapters explore the engineering of specific stem cell types with the protein of interest as well as results from studies of animal models and early-phase clinical trials. The use of cutting-edge molecular imaging techniques for a variety of tumor types is also integrated into the text. Coverage includes:An overview of stem cell types and their fate in models of cancerStem cell monotherapy in brain cancers, lung cancers, breast cancers, and other malignanciesThe use of stem cells in combination with other therapiesDiagnostic tracking of both stem cells and therapeutic molecules in cancer treatmentsPossible adverse effects of MSC on tumors, including details on tumor-initiating cells in certain tumor typesClear, concise, and up to date, Stem Cell Therapeutics for Cancer is a must-have resource for scientists and clinicians in stem cell research, cancer therapies, novel drug development, and molecular imaging, and for anyone wishing to learn about the unprecedented potential of stem cell therapeutics for various cancer types. From the Back Cover A single-source reference on the hot topic of stem cell therapeutics for cancerThis work offers a thorough, cohesive look at the state of the art of stem cell therapeutics for cancer, with an emphasis on the unique application of mesenchymal stem cells (MSC) and MSC-like cells as gene-delivery agents in cancer treatment. Edited by a leader in the field, the book brings together a wealth of information from this growing area of research, highlighting topics critical to the success of future therapies, including stem cell sources, tumor specificity, targeted therapeutics, visualizing the stem cell, and therapeutic agent pharmacokinetics.Organized in sections according to disease types, the chapters explore the engineering of specific stem cell types with the protein of interest as well as results from studies of animal models and early-phase clinical trials. The use of cutting-edge molecular imaging techniques for a variety of tumor types is also integrated into the text. Coverage includes:An overview of stem cell types and their fate in models of cancerStem cell monotherapy in brain cancers, lung cancers, breast cancers, and other malignanciesThe use of stem cells in combination with other therapiesDi