Cell Surface GRP78, a New Paradigm in Signal Transduction Biology - Image 1

£76.19

Academic Press Cell Surface GRP78, a New Paradigm in Signal Transduction Biology

Name: Cell Surface GRP78, a New Paradigm in Signal Transduction Biology
Brand: Academic Press
Price: 76.19 GBP
Availability: InStock

Biological Science

This is the usual price. Wait for it to drop, or tell us your number.

£76 today · usual range £0–£0 · best ever £36

NEW HERE?

Amazon shows you one price. We show you all of them.

Tosheroon watches Amazon prices so you don't have to. Every product on Amazon has a price history — we make it visible. Set the price you'd actually pay, and we'll email you the second it gets there. No app, no account, one email.

WHAT'S ON THIS PAGE

↓ Price chart
when this has been cheap or pricey

↓ Forecast
where the price is heading next

↓ Statistics
all-time high & low, recent range

↑ Price alert
name your number, we'll email you

Price History & Forecast

Grey patches = out of stock. Cheaper = lower on the chart. Hover for exact prices.

Last 613 days • 613 data points (No recent data available)

Historical

Generating forecast...

Price Distribution

Price distribution over 613 days • 5 price ranges

Days at Price

Current Price

Price Analysis

Most common range: £66-76 (177 days, 28.9%)

Price range: £36 - £86

Price levels: 5 price ranges over 613 days

Description

Cell Surface GRP78, a New Paradigm in Signal Transduction Biology presents a new paradigm that has emerged in the past decade with the discovery that various intracellular proteins may acquire new functions as cell surface receptors. Two very prominent examples are ATP synthase and GRP78. While the role of cell surface ATP synthase has been reviewed in various books, this book directs its attention to the story of cell surface GRP78. Edited by the researcher who identified cell surface expression of the molecular chaperone GRP78 as a major factor in prostate cancer and other malignancies Presents an in-depth treatment of the biological underpinnings of GRP78 and its connection to disease Provides four-color illustrations that facilitate the narrative Review Provides an overview of our understanding of the role of GRP78 as a major factor in cancer and other malignancies About the Author Studies from Pizzo’s laboratory identified cell surface expression of the molecular chaperone GRP78 as a major factor in prostate cancer and other malignancies. Cell surface GRP78 functions as a signaling receptor promoting tumor proliferation and suppressing apoptosis. Patients with a number of malignancies mount an autoimmune response to GRP78 and these antibodies, which bind to the NH2 terminal domains of GRP78, are receptor agonists whose appearance is a marker of poor prognosis. More recently, his lab has shown that antibodies directed against the COOH-terminal domain of GRP78 are receptor antagonists which may have therapeutic potential for treating patients whose tumors express GRP78 on the cell surface.

Product Specifications

Brand: Academic Press
Format: paperback
ASIN: 0128123516
Category: Books > Subjects > Science, Nature & Maths > Biological Sciences > Biological Science
Domain: Amazon UK
Release Date: 05 April 2018
Listed Since: 02 August 2017

Barcode

No barcode data available

Academic Press Cell Surface GRP78, a New Paradigm in Signal Transduction Biology

This is the usual price. Wait for it to drop, or tell us your number.

Price History & Forecast

Price Distribution

Price Analysis

Description

Product Specifications

Barcode

Similar Products You Might Like

Dissecting the Molecular Anatomy of Tissue (Principles and Practice)

A Clinical Guide for Cancer Prostate Patient

Cancer Drug Resistance: Overviews and Methods: 1395 (Methods in Molecular Biology, 1395)

Prostate Cancer: A Case Report

Springer - Molecular Genetics of Pancreatic Cancer Book

CONQUERING PROSTRATE CANCER: Practical strategies for prevention, diagnosis and treatment for men (Transformative Health Practices)

Recent Advances in Prostate Cancer: Basic Science Discoveries and Clinical Advances

Biopsy Interpretation of the Prostate (Biopsy Interpretation Series)

Androgen Action in Prostate Cancer

Metastasis Research Protocols: 1070 (Methods in Molecular Biology, 1070)

Precision Molecular Pathology of Prostate Cancer (Molecular Pathology Library)

Prostate Cancer, An Issue of Urologic Clinics (Volume 44-4) (The Clinics: Surgery, Volume 44-4)

Prostate Cancer: Science and Clinical Practice

Prostate Cancer Prevention: 202 (Recent Results in Cancer Research, 202)

Stem Cells in Regenerative Medicine: Methods and Protocols: 482 (Methods in Molecular Biology, 482)

Immune Mediators in Cancer: Methods and Protocols: 2108 (Methods in Molecular Biology, 2108)

PSA and Prostate Cancer (Cancer Etiology, Diagnosis and Treatments)

Prostate Cancer: Biochemistry, Molecular Biology and Genetics: 16 (Protein Reviews, 16)

Humana Cancer Cell Signaling: Methods and Protocols 218

Prostate Cancer: Translational and Emerging Therapies: 1 (Translational Medicine)

Cancer Biology

Prostate Cancer: Biochemistry, Molecular Biology and Genetics: 16 (Protein Reviews, 16)

Intercellular Communication in Cancer