Academic Press Liver Regeneration and Carcinogenesis: Molecular and Cellular Mechanisms

This work synthesizes current research into mechanisms of carcinogenesis and cell growth. Because of its ability to regenerate, many researchers use the liver as a model system to study these and other phenomena. Recently, advances have occurred in the understanding of hepatocyte growth regulation and the manner in which chemical agents and viruses alter these normal growth regulatory pathways in liver carcinogenesis. This work brings together current findings in a coherent manner, from a molecular point of view. Three sections cover in detail the areas of liver regeneration, liver carcinogenesis and liver tumour therapy. Synopsis This work synthesizes current research into mechanisms of carcinogenesis and cell growth. Because of its ability to regenerate, many researchers use the liver as a model system to study these and other phenomena. Recently, advances have occurred in the understanding of hepatocyte growth regulation and the manner in which chemical agents and viruses alter these normal growth regulatory pathways in liver carcinogenesis. This work brings together current findings in a coherent manner, from a molecular point of view. Three sections cover in detail the areas of liver regeneration, liver carcinogenesis and liver tumour therapy.