Springer Molecular Genetics of Liver Neoplasia Book

Primary liver cancer represents a significant global health challenge, ranking as the third most deadly cancer worldwide with approximately 500,000 annual deaths. As incidence rates continue to rise, particularly in the United States, understanding the biological foundations of these diseases becomes essential for medical professionals and researchers. This Springer publication provides a deep look into the molecular genetics of liver neoplasia, focusing on the major types of primary liver cancer, including hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC). The text explores how various risk factors contribute to the development of these malignancies. It covers the impact of hepatitis B virus (HBV), hepatitis C virus (HCV), and cirrhosis, as well as metabolic factors like diabetes, obesity, and metabolic diseases. By examining the relationship between inflammatory livers, oxidative stress, and viral hepatitis, this book serves as a vital resource for those studying the complex drivers of liver cancer. Whether you are researching the effects of toxins, alcohol consumption, or smoking on liver health, this volume provides the necessary scientific context for understanding modern oncology and disease progression.