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Academic Press Phosphodiesterase Inhibitors (Handbook of Immunopharmacology)

Name: Phosphodiesterase Inhibitors (Handbook of Immunopharmacology)
Brand: Academic Press
Price: 12.8 GBP
Availability: InStock

Allied Health Professions

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Description

Non-selective inhibitors of cyclic nucleotide phosphodiesterase (PDE), such as theophylline, have been used extensively since 1958. In the decade of the '70s, various PDE isoenzymes were defined which led to the development of the second generation of PDE inhibitors. Currently a variety of these new inhibitors are under test as potential anti-inflammatory drugs. During the past five years, molecular biology has revealed a superfamily of these phosphodiesterase isoenzymes. This book summarizes the present state of knowledge, as well as giving a comprehensive description of the compounds available. It will be invaluable for everyone who wants to choose the most suitable PDE inhibitor for their research or who is dealing with such drugs in a clinical setting. Utilizes actual testing and research of new PDE inhibitors Valuable for researchers and students alike From the Back Cover Non-selective inhibitors of cyclic nucleotide phospho-diesterase (PDE), such as theophylline, have been in clinical use since the last century and have been used extensively in research since the identification of PDE in 1958. Various PDE isoenzyme families have been defined, leading to the development of a second generation of PDE inhibitors with selectivity for certain families. Some of these new substances are under investigation as potential anti-inflammatory drugs. Recent progress in the molecular biology of PDEs has identified distinct individual isoenzymes within these families. This book summarizes the present state of knowledge, as well as providing a comprehensive description of available PDE inhibitors. It will be invaluable for everyone who wants to choose the most suitable PDE inhibitor for their research or who is dealing with such drugs in a clinical setting. About the Author Professor Clive P. Page, BSc PhD OBE HonFBPhS is a Professor of Pharmacology, King’s College London and Director of the Sackler Institute of Pulmonary Pharmacology, King’s College London. Clive’s main research interests are in the pharmacology of inflammation and respiratory disease and he has published over 250 scientific papers. Clive was the co-founder and previous Chairman of the Board of Verona Pharma plc, an AIM listed Company developing new drugs for the treatment of Respiratory Diseases. He is a Non Executive Director of and on boards of several companies. He was awarded the Society of Biology President’s Medal in 2012 for an outstanding contribution to the life sciences over the previous year. He is a Fellow of the Royal Society of Biology and an Honorary Fellow and President Elect of the British Pharmacological Society. In 2017, Clive was awarded an OBE for Services to Pharmacology.

Product Specifications

Brand: Academic Press
Format: hardcover
ASIN: 0122107209
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Allied Health Professions
Domain: Amazon UK
Release Date: 20 August 1996
Listed Since: 06 February 2007

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Academic Press Phosphodiesterase Inhibitors (Handbook of Immunopharmacology)

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