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Springer Thymus Transcriptome and Cell Biology - Springer Medical

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£129.99 £123.49 £126.09 £128.69 £131.29 £133.89 £136.49 28 July 2026 15 August 2026 02 September 2026 20 September 2026 08 October 2026
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Description

Thymus Transcriptome and Cell Biology provides an in-depth examination of genetic control in central immune tolerance and thymic development. This comprehensive volume explores thymic cellular components, their functional roles, and the distinctive gene expression profiles found in medullary thymic epithelial cells (mTECs) that facilitate self-representation within the thymus. The book thoroughly investigates the Autoimmune regulator (Aire) gene, associated mutations, and their manifestation in autoimmune diseases. It also addresses the critical importance of cell-cell interactions within the thymus and their implications for negative selection and elimination of autoreactive cells. Essential for medical practitioners, immunologists, and endocrinologists seeking detailed insights into thymic biology and immune system development.

Key Features

Covers thymus development and the cellular components responsible for maintaining central immune tolerance and self-representation.

Examines gene expression profiling and transcriptome analysis specific to medullary thymic epithelial cells (mTECs).

Discusses the Autoimmune regulator (Aire) gene, genetic mutations, and their direct links to autoimmune disease manifestation.

Explores cell-cell interactions within the thymus essential for negative selection and elimination of autoreactive lymphocytes.

Published by Springer, a leading academic publisher specialising in medical and scientific literature for healthcare professionals.

Product Specifications

Format
paperback
Domain
Amazon UK
Release Date
14 August 2020
Listed Since
02 August 2020

Barcode

No barcode data available

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