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Springer - The Blood Brain Barrier and Inflammation Book

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Description

This Springer volume from the Progress in Inflammation Research series provides a deep look at the blood-brain barrier (BBB) during both steady-state and inflamed conditions. It examines how the BBB separates the central nervous system (CNS) parenchyma from the bloodstream and the consequences when that separation is breached. The text explores how viruses, bacteria, parasites, and auto-aggressive immune cells penetrate the barrier to contribute to CNS inflammation. Readers will learn about the ways the BBB actively participates in neuroinflammation through the expression of cell adhesion molecules, the presentation of chemokines, and alterations to the barrier itself. This collection of reviews is an essential resource for understanding the mechanics of neuroinflammation and barrier function.

Key Features

This Springer publication offers a comprehensive collection of reviews regarding the role of the blood-brain barrier during steady-state and inflamed conditions.

The content examines how viruses, bacteria, parasites, and auto-aggressive immune cells penetrate the barrier to contribute to CNS inflammation.

Learn how the blood-brain barrier actively contributes to neuroinflammation through the presentation of chemokines and expression of cell adhesion molecules.

This volume explores the specific ways the BBB undergoes alterations to the barrier proper within the central nervous system.

Part of the Progress in Inflammation Research series, this book focuses on the relationship between the bloodstream and the CNS parenchyma.

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