£93.65

Springer Targeting the Wnt Pathway in Cancer - Springer Medical Reference

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Description

Inappropriate activation of the Wnt signaling pathway drives tumour initiation and progression across numerous cancer types, making it a critical therapeutic target for researchers and clinicians. This Springer medical reference explores the multiple mechanisms responsible for pathway activation in tumour cells, including Wnt ligand overexpression, APC and Axin tumour suppressor inactivation, and beta-catenin mutation. The book provides a comprehensive overview of the Wnt pathway as a therapeutic target and documents the major recent efforts in developing potent Wnt pathway antagonists for clinical use. Written for investigators in academia and industry, this essential resource addresses the latest advances in targeting this fundamental cancer signaling pathway and offers practical insights into therapeutic development strategies.

Key Features

Springer-published medical reference examining Wnt pathway activation mechanisms in human cancer biology.

Covers multiple pathways to tumour development including Wnt ligand overexpression and tumour suppressor inactivation.

Provides overview of Wnt pathway antagonists and recent therapeutic development efforts in oncology.

Designed for academic researchers and pharmaceutical industry professionals working in cancer therapeutics.

Product Specifications

Format
hardcover
Domain
Amazon UK
Release Date
28 January 2011
Listed Since
01 October 2010

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