£93.65

Springer - Targeting the Wnt Pathway in Cancer - Oncology Book

Name: Springer - Targeting the Wnt Pathway in Cancer - Oncology Book
Brand: Springer
Price: 93.65 GBP
Availability: InStock

Oncology

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Description

Inappropriate activation of the Wnt signaling pathway is observed in many human cancers and is sufficient to drive tumor initiation and progression in numerous contexts. This professional resource from Springer provides a detailed overview of the Wnt pathway and its role in oncological development. Readers will find information regarding the multiple mechanisms responsible for pathway activation in tumor cells. This includes the overexpression of Wnt ligands, the inactivation of APC and Axin tumor suppressors, and the mutation of beta-catenin. As researchers in both academia and industry focus on the development of potent Wnt pathway antagonists for therapeutic use, this text serves as a fundamental reference for understanding these biological processes. This book is designed for medical professionals and researchers interested in internal medicine and oncology. It covers the fundamental biological drivers of cancer and the ongoing efforts to develop new therapeutic strategies to combat tumor progression.

Key Features

Explores how Wnt signaling pathway activation drives tumor initiation and progression in various human cancers.

Covers specific mechanisms of pathway activation including Wnt ligand overexpression and beta-catenin mutation.

Examines the role of APC and Axin tumor suppressor inactivation in the development of cancer cells.

Provides an overview of the current efforts in academia and industry to develop Wnt pathway antagonists for therapy.

Serves as a specialized resource for oncology professionals and medical researchers studying internal medicine.

Product Specifications

Brand: Springer
Format: hardcover
ASIN: 1441980229
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Internal Medicine > Diseases & Disorders > Oncology
Domain: Amazon UK
Release Date: 28 January 2011
Listed Since: 01 October 2010

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Springer - Targeting the Wnt Pathway in Cancer - Oncology Book

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