£129.99

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Springer Ryanodine Receptors: Structure, Function & Clinical Disease

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Description

This comprehensive volume brings together leading researchers who have dedicated their careers to understanding ryanodine receptors, essential calcium-release channels in cardiac and skeletal muscle. Written by Drs. Xander Wehrens and Andrew Marks, the book progresses systematically from basic gene family organisation and primary structure through three-dimensional protein architecture to regulatory mechanisms and physiological function. Subsequent chapters explore mutations causing disease and adaptive responses to dysfunction, providing clinicians and researchers with critical insights into pathophysiology. The work includes emerging discoveries on accessory protein control of ryanodine receptors, offering practical knowledge for understanding cardiovascular disease mechanisms and potential therapeutic approaches. Part of the Springer Developments in Cardiovascular Medicine series, this text bridges fundamental molecular biology with clinical application.

Key Features

Authored by Drs. Xander Wehrens and Andrew Marks, leading experts in ryanodine receptor research and cardiovascular physiology.

Covers ryanodine receptor gene family organisation, primary structure, and detailed three-dimensional protein architecture.

Examines regulation, physiological function, and the role of accessory proteins in controlling ryanodine receptor activity.

Includes chapters on mutations causing disease and mechanisms of adaptation to ryanodine receptor dysfunction in clinical settings.

Published by Springer as volume 254 in the Developments in Cardiovascular Medicine series for medical professionals.

Product Specifications

Format
paperback
Domain
Amazon UK
Release Date
01 December 2014
Listed Since
02 December 2014

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