£122.85

Springer Proteoglycans in Stem Cells: From Development to Cancer

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Description

Proteoglycans in Stem Cells: From Development to Cancer provides a state-of-the-art compendium regarding the role of proteoglycans and glycosaminoglycans during development and in cancer. As part of the extracellular matrix, these components act as multifunctional modulators of growth factor, cytokine, integrin, and morphogen signaling. These processes determine the self-renewal, senescence, and differentiation of stem cells during development. This volume explores how proteoglycans modulate cell adhesion and migration. It also suggests directions for novel therapeutic and biotechnological applications within the field of stem cell biology. This book serves as a specialized resource for those studying the biological mechanisms of the extracellular matrix and its impact on cellular behavior in both healthy development and disease states.

Key Features

Covers the role of proteoglycans and glycosaminoglycans during development and in cancer research.

Explains how these components modulate growth factor, cytokine, integrin, and morphogen signaling.

Examines the influence of the extracellular matrix on stem cell self-renewal, senescence, and differentiation.

Discusses how proteoglycans affect cell adhesion and migration processes.

Provides insights into novel therapeutic and biotechnological applications in stem cell biology.

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