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Springer Prokaryotic Toxin-Antitoxins - Springer Research Overview

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Description

Prokaryotic Toxin-Antitoxins provides the first comprehensive overview of this rapidly expanding research field, exploring how toxin-antitoxin (TA) genes function in bacterial and archaeal systems. Originally discovered on plasmids three decades ago, TA genes are now recognised as highly abundant throughout prokaryotic chromosomes. This authoritative work explains how antitoxin proteins combine with and neutralise cognate toxins, and examines the critical role these systems play in inhibiting protein synthesis and cell growth to induce dormancy and multidrug tolerance, also known as persistence. The book addresses the remarkable expansions observed in TA gene families across various species, making it essential reading for researchers, microbiologists, and healthcare practitioners studying bacterial physiology, antibiotic resistance, and molecular pathology.

Key Features

Prokaryotic Toxin-Antitoxins by Springer delivers the first comprehensive overview of toxin-antitoxin gene discoveries and their mechanisms in bacterial and archaeal chromosomes.

Explores how TA genes code for antitoxin proteins that neutralise cognate toxins and induce bacterial dormancy and multidrug tolerance responses.

Covers the dramatic expansions of TA gene families across different prokaryotic species, revealing the evolutionary significance of these systems.

Provides essential insights into toxin inhibition of protein synthesis and cell growth, directly relevant to understanding bacterial persistence and antibiotic resistance.

Product Specifications

Format
paperback
Domain
Amazon UK
Release Date
09 November 2014
Listed Since
05 November 2014

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No barcode data available

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